2. Infection

Infection

Infection

Related Products

PDF 70.44 MB

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N16443
    Sporminarin A 915403-42-8 98%
    Sporminarin A (Compound 1), a polyketide, is a microbial secondary metabolite. Sporminarin A can be isolated from the Sporormiella minimoides. Sporminarin A has significant antifungal activity against Aspergillus flavus with an MIC50 of 25  μg/mL. Sporminarin A also has antibacterial activity against Staphylococcus aureus (ATCC 29213) and Candida albicans (ATCC 14053).
    Sporminarin A
  • HY-N16444
    Sporminarin B 915403-43-9 98%
    Sporminarin B is an antibacterial and antifungal agent. Sporminarin B exhibits inhibitory activity against microorganisms such as Candida albicans and Staphylococcus aureus.
    Sporminarin B
  • HY-N16445
    Strevertene A 235090-14-9
    Strevertene A ((-)-Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants.
    Strevertene A
  • HY-N16446
    Stromemycin 345295-46-7 98%
    Stromemycin is a stromelysin inhibitor. Stromemycin exhibits weak antibacterial activity against Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and Bacillus subtilis when used alone. Stromemycin shows a significant increase in antibacterial efficacy when combined with Compound 5. Stromemycin does not possess a significant cell-killing effect on HCT-116 cells.
    Stromemycin
  • HY-N16448
    Xanthoascin 61391-08-0 98%
    Xanthoascin (Compound 1) is a natural phenolic metabolite with strong anti plant pathogen activity. Xanthoascin can be extracted from the solid fermentation product of endophytic fungus Aspergillus sp. IFB-YXS isolated from Ginkgo biloba leaves. Xanthoascin has a MIC of 0.3125 µg/mL against Clavibacter michiganense subsp. Sepedonicus and moderate inhibitory activity against other pathogens (MIC = 5-20 µg/mL). Xanthoascin can disrupt the permeability of bacterial cell membranes, leading to nucleic acid leakage.
    Xanthoascin
  • HY-N16451
    Asperindole E 98%
    Asperindole E is an indole-diterpene alkaloid that can be isolated from the coral-associated fungi Aspergillus candidus. Asperindole E exhibits no significant regulatory activity in the model of primary cultured cortical neuronal hyperexcitation.
    Asperindole E
  • HY-N16452
    Asperindole F 98%
    Asperindole F is an indole-diterpene alkaloid that can be isolated from the coral-associated fungi Aspergillus candidus. Asperindole F exhibits no significant regulatory activity in the model of primary cultured cortical neuronal hyperexcitation.
    Asperindole F
  • HY-N16457
    5,6-Dihydro-6-hydroxypenicillic acid 1661837-02-0
    5,6-Dihydro-6-hydroxypenicillic acid (Compound 6) is a microbial secondary metabolite. 5,6-Dihydro-6-hydroxypenicillic acid can be isolated from the endophytic fungus Talaromyces sp. CPCC 400783 of Reynoutria japonica Houtt. 5,6-Dihydro-6-hydroxypenicillic acid has antiviral activity against influenza A virus with an IC50 of 65.45 μM.
    5,6-Dihydro-6-hydroxypenicillic acid
  • HY-N16458
    FI-3 1316171-50-2
    FI-3 is a polycyclic tetramate macrolactam biosynthetic intermediate found in Streptomyces sp. SPB78. FI-3 is promising for research of antibiotics.
    FI-3
  • HY-N16461
    Albomycin ε 12676-10-7
    Albomycin ε is a siderophore-antibiotic conjugate targeting bacterial ribosomes (MIC values:>512 μg/mL). Albomycin ε is promising for research of Streptococcus pneumoniae and Staphylococcus aureus infections.
    Albomycin ε
  • HY-N16473
    14,15-Epoxyazadiradione 58525-91-0 98%
    14,15-Epoxyazadiradione is a triterpenoid found in Azadirachta indica. Azadirachta indica shows anti-infection, anti-inflammatory and anticancer activities. Azadirachtin H can be used for the researches of cancer, infection and inflammation.
    14,15-Epoxyazadiradione
  • HY-N16479
    Azadirachtin I 134788-16-2
    Azadirachtin I is an insecticide targeting insect growth and development-related pathways (e.g., ecdysone signaling pathway, chitin synthesis pathway). Azadirachtin I inhibits chitin synthesis and disrupting intestinal function by interfering with the growth and development processes of insect larvae such as molting and pupation, increasing insect mortality and reducing adult fecundity. Azadirachtin I is promising for research of agricultural pests, such as Lepidoptera, Coleoptera.
    Azadirachtin I
  • HY-N16480
    Lindetannin 651750-97-9 98%
    Lindetannin (Lindetannin trimer) is an A-type trimer of proanthocyanidin (HY-N0794) found in the bark of Cinnamomum trees. Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy.
    Lindetannin
  • HY-N16516
    Velutinam 146428-62-8 98%
    Velutinam is an alkaloid. Velutinam can be isolated from twigs of Uvaria grandiflora Roxb. Velutinam shows antioxidant activity. Velutinam can be used in the research of bacterial infections.
    Velutinam
  • HY-N16519
    [6]-Gingerdiol 154905-69-8 98%
    [6]-Gingerdiol is an antifungal agent. [6]-Gingerdiol can be isolated from Zingiber officinale. [6]-Gingerdiol shows antifungal activity against M. gypseum with a MLC value of 422 μg/mL.
    [6]-Gingerdiol
  • HY-N16526
    Juncatrin B 2306413-51-2
    Juncatrin B is a type of dihydrophenanthrene compound. Juncatrin B exhibits inhibitory activity against both Methicillin (HY-121544)-sensitive Staphylococcus aureus (MSSA) and Methicillin-resistant Staphylococcus aureus (MRSA). Juncatrin B can inhibit the formation of biofilms in MSSA and MRSA. Juncatrin B has no significant activity against Gram-negative bacteria. Juncatrin B can be used in the research of anti-Staphylococcus aureus.
    Juncatrin B
  • HY-N16541
    (-)-Mecambridine 31098-60-9
    (-)-Mecambridine (Compound 2) is a retroprotoberberine alkaloid found in Papaver pseudocanescens M. Pop. (-)-Mecambridine has weak inhibitory activity against poliovirus type 1.
    (-)-Mecambridine
  • HY-N16542
    n-Butylorsellinate 31489-30-2 98%
    N-Butylorsellinate is a butyl thicoline acid ester that can be found in fungi belonging to the Stereum genus. N-Butylorsellinate exhibits significant larvicide activity.
    n-Butylorsellinate
  • HY-N16586
    Apigenin 7,4'-di-O-alloside 95693-63-3 98%
    Apigenin 7,4'-di-O-alloside is a type of flavonoid glycoside compound that exhibits anti-SARS-CoV-2 virus activity.
    Apigenin 7,4'-di-O-alloside
  • HY-N16590
    Diphylloside A 113558-11-5 98%
    Diphylloside A is a flavonoid compound with antioxidant activity. Diphylloside A exhibits significant antibacterial activity against Pseudomonas aeruginosa.
    Diphylloside A
Cat. No. Product Name / Synonyms Application Reactivity