2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N9362R
    Emodinanthrone (Standard) 491-60-1
    Pro-xylane (Standard) is the analytical standard of Pro-xylane. This product is intended for research and analytical applications. Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC50=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury.
    Emodinanthrone (Standard)
  • HY-N9438R
    Lactucin (Standard) 1891-29-8
    Lactucin (Standard) is the analytical standard of Lactucin. This product is intended for research and analytical applications. Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities[4].
    Lactucin (Standard)
  • HY-N9448R
    Lacto-N-tetraose (Standard) 14116-68-8
    Ethyl 2-chloronicotinate (Standard) is the analytical standard of Ethyl 2-chloronicotinate. This product is intended for research and analytical applications. Ethyl 2-chloronicotinate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Lacto-N-tetraose (Standard)
  • HY-N9971R
    Hentriacontane (Standard) 630-04-6
    Hentriacontane (Standard) is the analytical standard of Hentriacontane. This product is intended for research and analytical applications. Hentriacontane is a long-chain alkane. Hentriacontane exerts anti-inflammatory effects by inhibiting the NF-κB pathway. Hentriacontane has anti-inflammatory, antitumor and antibacterial activities.
    Hentriacontane (Standard)
  • HY-NP0220
    Chicken Yolk Immunoglobulin 98%
    Chicken Yolk Immunoglobulin (IgY) is a natural antibody extracted from the yolk of immune hens. It has high stability and is widely used in antiviral, immunoassay and other fields.
    Chicken Yolk Immunoglobulin
  • HY-NP0222
    Apolactoferrin 98%
    Apolactoferrin is an iron-free form of lactoferrin with antiparasitic activity. Apolactoferrin is an iron-binding protein.
    Apolactoferrin
  • HY-P0018C
    Pepstatin acetate 28575-34-0 98%
    Pepstatin (Pepstatin A) acetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin acetate also inhibits HIV protease.
    Pepstatin acetate
  • HY-P0018R
    Pepstatin (Standard) 26305-03-3 98%
    Pepstatin (Standard) is the analytical standard of Pepstatin. This product is intended for research and analytical applications. Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease[1][2].
    Pepstatin (Standard)
  • HY-P0263R
    Dermaseptin (Standard) 136212-91-4
    Kanamycin (sulfate) (Standard) is the analytical standard of Kanamycin (sulfate). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia.
    Dermaseptin (Standard)
  • HY-P0269A
    Magainin 1 TFA 98%
    Magainin 1 TFA (Magainin I TFA) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 TFA exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria.
    Magainin 1 TFA
  • HY-P0272A
    Peptide T TFA 1610056-01-3 98%
    Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.
    Peptide T TFA
  • HY-P10038
    mP6 2700321-79-3 98%
    mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells.
    mP6
  • HY-P10150
    IN-2-LF 749879-64-9 98%
    IN-2-LF is an inhibitor of lethal factor. IN-2-LF also inhibits furin with an IC50 of 2 μM. IN-2-LF enhances protection against anthrax lethal toxin when in combination with D6R.
    IN-2-LF
  • HY-P10159
    DJK-5 1809102-71-3 98%
    Diplacol ia a natural compound from from Mimulus clevelandi and shows potent inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide production.
    DJK-5
  • HY-P10160
    Cathelicidin-2 (chicken) 1149347-67-0 98%
    Cathelicidin-2 chicken is antimicrobial peptide. Cathelicidin-2 chicken shows potent bactericidal and fungicidal activity against chicken-specific salmonella isolates.
    Cathelicidin-2 (chicken)
  • HY-P10182
    Angiotensin III antipeptide 133605-55-7 98%
    Angiotensin III antipeptide is a peptide antibiotic.
    Angiotensin III antipeptide
  • HY-P10208
    RKH 98%
    PKH is a TLR4 antagonist. PKH is a novel tripeptide and can be isolated from Akkermansia muciniphila. RKH reduces sepsis-induced inflammatory cell activation and proinflammatory factor overproduction.
    RKH
  • HY-P10209
    Cilagicin 98%
    Cilagicin, a dodeca-lipodepsipeptide, is a Gram-positive active antibiotic. Cilagicin has a dual polyprenyl phosphate binding mechanism that impedes resistance development.
    Cilagicin
  • HY-P10210
    Paenilagicin 98%
    Paenilagicin is a Gram-positive active antibiotic with a unique diphosphorylated prenyl binding mechanism that does not induce drug resistance. Paenilagicin exhibits a MIC value of 2 μg/mL against multidrug-resistant Gram-positive bacteria.
    Paenilagicin
  • HY-P10211
    Virgilagicin 98%
    Virgilagicin is a Gram-positive active antibiotic that has a dual polyprenyl phosphate binding mechanism that impedes resistance development.
    Virgilagicin
Cat. No. Product Name / Synonyms Application Reactivity