2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P990304B
    Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) 98%
    Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) is a mouse-derived IgG1 κ antibody inhibitor that targets mouse 4-1BBL/CD137L. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) is a chimeric version of the original TKS-1 antibody (HY-P990304). The variable domain sequences are identical to the original TKS-1 but the constant region sequences have been switched from rat IgG2a to mouse IgG1. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) contains a D265A mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) reacts with mouse 4-1BB ligand (4-1BBL). Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) can be used for the researches of cancer, infection, inflammation and immunology.
    Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1)
  • HY-W001957R
    Glurate (Standard) 3128-06-1
    Glurate (Standard) is the analytical standard of Glurate (HY-W001957). This product is used for research and analytical applications. Glurate (4-Acetylbutyric acid) is an acylating agent. Glurate can be used in the development of antiviral compounds, especially those targeting retroviruses such as herpes virus and HIV. Glurate can be used in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid.
    Glurate (Standard)
  • HY-W001963R
    Pyrrole-2-carboxylic acid (Standard) 634-97-9
    Pyrrole-2-carboxylic acid (Standard) is the analytical standard of Pyrrole-2-carboxylic acid (HY-W001963). This product is intended for research and analytical applications. sp. Nov. Pyrrole-2-carboxylic acid shows antibacterial activity and inhibits biofilm formation. Pyrrole-2-carboxylic acid serves as a precursor for various pyrrole derivatives like Clorobiocin (HY-123515), Coumermycin A1 (HY-N7452) in biosynthetic processes.
    Pyrrole-2-carboxylic acid (Standard)
  • HY-W002116S
    Methyl syringate-d6 1182838-09-0 98%
    Methyl syringate-d6 is the deuterium labeled Methyl syringate. Methyl syringate is a selective TRPA1 agonist. Methyl syringate regulates food intake and gastric emptying through a TRPA1-mediated pathway. Methyl syringate is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a chemical marker of Asphodel monofloral honey. Methyl syringate contributes to the antibacterial activity of honey. Methyl syringate inhibits aflatoxin production. Methyl syringate can contribute to weight suppression. Methyl syringate can be studies for cancer prevention (e.g. lung cancer), suppression of hypoxia-induced inflammatory response and tumorigenesis.
    Methyl syringate-d6
  • HY-W003467R
    Rabeprazole Sulfide (Standard) 117977-21-6 98%
    Rabeprazole Sulfide (Standard) is the analytical standard of Rabeprazole Sulfide (HY-W003467). This product is intended for research and analytical applications. Rabeprazole Sulfide is a sulfide metabolite of Rabeprazole (HY-B0656). Rabeprazole Sulfide inhibits Helicobacter pylori motility. Rabeprazole Sulfide can be used for the research of Helicobacter pylori infection.
    Rabeprazole Sulfide (Standard)
  • HY-W004282R
    Undecanoic acid (Standard) 112-37-8 99.83%
    Undecanoic acid (Standard) (Undecanoate (Standard)) is the analytical standard of Undecanoic acid (HY-W004282). This product is intended for research and analytical applications. Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
    Undecanoic acid (Standard)
  • HY-W004291R
    Methyl arachidate (Standard) 1120-28-1
    Methyl arachidate (Standard) is the analytical standard of Methyl arachidate (HY-W004291). This product is intended for research and analytical applications. Methyl arachidate (Methyl icosanoate) is a component of lipid mixtures. Methyl arachidate can be isolated from flowering plants. Methyl arachidate inhibits LTA4H. Methyl arachidate shows no antifeedant activity against Leptinotarsa decemlineata.
    Methyl arachidate (Standard)
  • HY-W004292R
    1-Undecanol (Standard) 112-42-5 98%
    1-Undecanol (Standard) (Undecyl alcohol (Standard)) is an analytical reference standard for 1-Undecanol (HY-W004292). This product is used for research and analytical applications. 1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps.
    1-Undecanol (Standard)
  • HY-W004294S
    1-Tetradecanol-d29 284474-78-8 98%
    1-Tetradecanol-d29 is the deuterium labeled 1-Tetradecanol. 1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity.
    1-Tetradecanol-d29
  • HY-W005327R
    1-Hydroxy-2-butanone (Standard) 5077-67-8
    1-Hydroxy-2-butanone (Standard) is the analytical standard of 1-Hydroxy-2-butanone. This product is intended for research and analytical applications. 1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects[1][2].
    1-Hydroxy-2-butanone (Standard)
  • HY-W007771R
    Acridone (Standard) 578-95-0 99.76%
    Acridone (Standard) is the analytical standard of Acridone. This product is intended for research and analytical applications. Acridone is an organic compound based on the acridine skeleton. Acridone has antibacterial, antimalarial, antiviral and anti neoplastic activities.
    Acridone (Standard)
  • HY-W008226R
    Phloracetophenone (Standard) 480-66-0 98%
    Oxprenolol (hydrochloride) (Standard) is the analytical standard of Oxprenolol (hydrochloride). This product is intended for research and analytical applications. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.
    Phloracetophenone (Standard)
  • HY-W008566R
    Norharmane (Standard) 244-63-3
    Norharmane (Standard) is the analytical standard of Norharmane. This product is intended for research and analytical applications. Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings.
    Norharmane (Standard)
  • HY-W008923R
    Doxycycline monohydrate (Standard) 17086-28-1
    Doxycycline monohydrate (Standard) is the analytical standard of Doxycycline monohydrate (HY-W008923). Doxycycline monohydrate is an orally active highly lipophilic, tissue-permeable MMP inhibitor with broad-spectrum antibacterial activity. Doxycycline monohydrate is also a semi-synthetic antibiotic with chelating properties, which blocks bacterial protein synthesis and inhibits extracellular matrix degradation through interactions with zinc and calcium atoms. Doxycycline monohydrate also inhibits mitochondrial biogenesis, translation, and the expression of respiratory chain proteins. Doxycycline monohydrate induces apoptosis, inhibits autophagy and EMT, downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells. Doxycycline monohydrate also promotes the survival and self-renewal of embryonic stem cells and neural stem cells, and reduces the frequency of medium changes in culture. Doxycycline monohydrate has been applied in studies related to breast cancer, prostate cancer, bladder cancer, and other cancers.
    Doxycycline monohydrate (Standard)
  • HY-W008927A
    (Z)-Fluoxastrobin 887973-21-9 98%
    (Z)-Fluoxastrobin is fungicide agent. (Z)-Fluoxastrobin has excellent control of important seed and soilborne pathogens.
    (Z)-Fluoxastrobin
  • HY-W009326S
    Laurocapram-15N 98%
    Laurocapram-15N is a deuterated labeled Laurocapram. Laurocapram is a chemical penetration enhancer that increases the permeability of compounds through the skin and mucous membranes, thereby improving their local or systemic efficacy. Laurocapram improves the skin permeability of a variety of hydrophilic and lipophilic compounds.
    Laurocapram-15N
  • HY-W009783A
    Deoxymannojirimycin hydrochloride 84444-90-6 98%
    Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor. Deoxymannojirimycin hydrochloride has antiviral activity against HIV‐1 strains . Deoxymannojirimycin hydrochloride increases high mannose structures. Deoxymannojirimycin hydrochloride can be used for the study of liver cancer and colon cancer.
    Deoxymannojirimycin hydrochloride
  • HY-W009886S
    3,4,5-Trimethoxybenzaldehyde-d3 1219805-17-0 98%
    3,4,5-Trimethoxybenzaldehyde-d3 is the deuterium labeled 3,4,5-Trimethoxybenzaldehyde (HY-W009886). 3,4,5-Trimethoxybenzaldehyde is a derivative of benzaldehyde. 3,4,5-Trimethoxybenzaldehyde has antimicrobial activity. 3,4,5-Trimethoxybenzaldehyde is also an important intermediate for the synthesis of various drugs, such as Trimethoprim (HY-B0510).
    3,4,5-Trimethoxybenzaldehyde-d3
  • HY-W010235R
    3,5-Dimethoxytoluene (Standard) 4179-19-5
    3,5-Dimethoxytoluene (Standard) is the analytical standard of 3,5-Dimethoxytoluene. This product is intended for research and analytical applications. 3,5-Dimethoxytoluene, a methylated phenolic derivative, is one of characteristic scent compounds emitted from flowers of most rose varieties. 3,5-Dimethoxytoluene shows significant fumigant toxicity against L. serricorne and L. bostrychophila with LC50 values of 4.99 mg/L air and 0.91 mg/L air, respectively[1].
    3,5-Dimethoxytoluene (Standard)
  • HY-W010520R
    Methylisothiazolinone (Standard) 2682-20-4 98%
    Methylisothiazolinone (Standard) is the analytical standard of Methylisothiazolinone. Methylothiazolinone is a fungicide and preservative, as well as a sensitizer. Methylisothiazolinone can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce cell apoptosis and inflammatory response. Methylisothiazolinone can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone can cause mitochondrial damage in the endothelium of rat cerebral blood vessels.
    Methylisothiazolinone (Standard)
Cat. No. Product Name / Synonyms Application Reactivity