Methyl syringate-d6
Methyl syringate-d6 is the deuterium labeled Methyl syringate. Methyl syringate is a selective TRPA1 agonist. Methyl syringate regulates food intake and gastric emptying through a TRPA1-mediated pathway. Methyl syringate is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a chemical marker of Asphodel monofloral honey. Methyl syringate contributes to the antibacterial activity of honey. Methyl syringate inhibits aflatoxin production. Methyl syringate can contribute to weight suppression. Methyl syringate can be studies for cancer prevention (e.g. lung cancer), suppression of hypoxia-induced inflammatory response and tumorigenesis.
For research use only. We do not sell to patients.
- CAS No.: 1182838-09-0
- Formula: C10H6D6O5
- Molecular Weight:218.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1182838-09-0
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Unlabeled Cas 884-35-5
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Molecular Weight 218.24
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Formula C10H6D6O5
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SMILES
COC(C1=CC(OC([2H])([2H])[2H])=C(C(OC([2H])([2H])[2H])=C1)O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kim MJ, et al. The TRPA1 agonist, methyl syringate suppresses food intake and gastric emptying. PLoS One. 2013 Aug 218(8):e71603. [Content Brief]
[2]. Rosado T, et al. Methyl syringate: an efficient phenolic mediator for bacterial and fungal laccases. Bioresour Technol. 2012 Nov124:371-8. [Content Brief]
[3]. Tuberoso CI, et al. Methyl syringate: a chemical marker of asphodel (Asphodelus microcarpus Salzm. et Viv.) monofloral honey. J Agric Food Chem. 2009 May 13;57(9):3895-900. [Content Brief]
[4]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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