2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N14752
    Hydroxymycotrienin A 178550-61-3 98%
    Hydroxymycotrienin A is an Ansa antibiotic. Hydroxymycotrienin A has the activity of inhibiting human neck tumor cell line, and its inhibitory effect on human papillomavirus (HPV) gene positive neck tumor cells (such as HeLa, CaSKi, SiHa, etc.) is stronger than HPV gene negative cells.
    Hydroxymycotrienin A
  • HY-N14753
    Juglomycin A 38637-88-6 98%
    Juglomycin A has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg.
    Juglomycin A
  • HY-N14754
    Juglomycin B 38637-89-7 98%
    Juglomycin B has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg.
    Juglomycin B
  • HY-N14755
    Juvenimicin A2 61417-47-8 98%
    Juvenimicin A2 can resist Gram-positive bacteria and individual Gram-negative bacteria.
    Juvenimicin A2
  • HY-N14759
    Matlystatin B 140923-32-6 98%
    Matlystatin B is a type IV collagenase inhibitor. Matlystatin B has anti-Gram-positive bacteria effect.
    Matlystatin B
  • HY-N14760
    Leucomycin A9 18361-49-4 98%
    Leucomycin A9 is a macrolide antibiotic. Leucomycin A9 has strong anti-Gram-positive bacterial effect, and also has an effect on spirochetes, Rickettsium and Chlamydia.
    Leucomycin A9
  • HY-N14761
    Matlystatin D 140638-25-1 98%
    Matlystatin D is a metalloproteinase (MMP) inhibitor.
    Matlystatin D
  • HY-N14762
    Leucomycin V 22875-15-6 98%
    Leucomycin V is a macrolide antibiotic. Leucomycin V has strong anti-Gram-positive bacterial effect, and also has an effect on spirochetes, Rickettsium and Chlamydia.
    Leucomycin V
  • HY-N14764
    2-Hydroxyaclacinomycin A 79127-36-9 98%
    2-Hydroxyaclacinomycin A is an anthracycline antibiotic. 2-Hydroxyaclacinomycin A has the activity of inhibiting leukemia L-1210 cells, and the IC50 for RNA and DNA synthesis is 0.10 μg/mL and 0.95 μg/mL, respectively.
    2-Hydroxyaclacinomycin A
  • HY-N14768
    O-Demethylpaulomycin A 113603-74-0 98%
    O-Demethylpaulomycin A is an antibiotic with antibacterial activity. O-Demethylpaulomycin A can inhibit Gram-positive bacteria, especially Staphylococcus aureus.
    O-Demethylpaulomycin A
  • HY-N14770
    Matlystatin E 140638-26-2 98%
    Matlystatin E is a metalloproteinase (MMP) inhibitor.
    Matlystatin E
  • HY-N14771
    Matlystatin F 140667-42-1 98%
    Matlystatin F is a metalloproteinase (MMP) inhibitor.
    Matlystatin F
  • HY-N14772
    Laccaridione A 320369-80-0 98%
    Laccaridione A can inhibit the activity of antiserine protease. Laccaridione A inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50s of 14.7 μg/mL, 2.5 μg/mL, 18.8 μg/mL, 7.2 μg/mL and 18.2 μg/mL, respectively.
    Laccaridione A
  • HY-N14773
    Laccaridione B 320369-81-1 98%
    Laccaridione B can inhibit the activity of antiserine protease. Laccaridione B inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50s of 10.9 μg/mL, 5.1 μg/mL, 8.4 μg/mL, 5.7 μg/mL and 3.0 μg/mL, respectively. Laccaridione B also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50s of 2.4 μg/mL, 1.8 μg/mL and 13.9 μg/mL, respectively.
    Laccaridione B
  • HY-N14774
    Lactoquinomycin B 101342-94-3 98%
    Lactoquinomycin B is a quinone antibiotic. Lactoquinomycin B has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin B inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively.
    Lactoquinomycin B
  • HY-N14775
    Lavanduquinocin 167114-85-4 98%
    Lavanduquinocin is a protective agent of nerve cells and has the effect of reducing L-glutamate on cytotoxicity of neuronal hybridoma N18-RE-105 with an ED50 of 15.5 nM.
    Lavanduquinocin
  • HY-N14777
    Hydroxyakalone 182056-35-5 98%
    Hydroxyakalone is an inhibitor of Xanthosine oxidase (XOD, EC 1.2.3.2), with an IC50 of 4.6 μM.
    Hydroxyakalone
  • HY-N14779
    Mureidomycin A 114797-04-5 98%
    Mureidomycin A is an antibiotic with anti-Pseudomonas aeruginosa activity.
    Mureidomycin A
  • HY-N14780
    Pochonin D 544712-82-5 98%
    Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affects the homeostasis, folding and assembly processes of viral proteins, and reduces the replication capacity of viruses. Pochonin D is a copper ion carrier that can induce cuproptosis in triple-negative breast cancer cells by targeting PRDX1. Pochonin D reduces the infiltration of inflammatory cells, decreases the secretion of inflammatory cytokines such as TNF-α and IL-1β, and alleviates inflammatory responses. Pochonin D is a promising candidate for research on human rhinovirus (HRV) infection and cancer.
    Pochonin D
  • HY-N14782
    10-Decarbomethoxyaclacinomycin A 76264-91-0 98%
    10-Decarbomethoxyaclacinomycin A is an anthracycline antibiotic can be produced by Streptomyces galilaeus MA144-Mlt mutant strain KE303. 10-Decarbomethoxyaclacinomycin A has antibacterial activities.
    10-Decarbomethoxyaclacinomycin A
Cat. No. Product Name / Synonyms Application Reactivity