2. Infection

Infection

Infection

Related Products

PDF 70.44 MB

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-100943R
    Cinanserin hydrochloride (Standard) 54-84-2 98%
    Cinanserin (hydrochloride) (Standard) is the analytical standard of Cinanserin (hydrochloride) (HY-100943). This product is intended for research and analytical applications. Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1 receptor (Ki of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
    Cinanserin hydrochloride (Standard)
  • HY-101000R
    Clazuril (Standard) 101831-36-1
    Clazuril (Standard) is the analytical standard of Clazuril. This product is intended for research and analytical applications. Clazuril (R62690) has a coccidiocidal effect on the asexual and sexual developmental stages of both Eimeria species, resulting in a complete interruption of the life cycle.
    Clazuril (Standard)
  • HY-101040A
    Telacebec ditosylate 1566517-83-6 98%
    Telacebec ditosylate is a midazopyridine amide compound. Telacebec ditosylate is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium.
    Telacebec ditosylate
  • HY-101293R
    VU0359595 (Standard) 1246303-14-9 98%
    VU0359595 (Standard) is the analytical standard of VU0359595 (HY-101293). This product is intended for research and analytical applications. VU0359595 (CID-53361951; ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 μM). VU0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases.
    VU0359595 (Standard)
  • HY-101397R
    Allopurinol riboside (Standard) 16220-07-8
    Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.
    Allopurinol riboside (Standard)
  • HY-101409S
    O-Acetylserine-13C 98%
    O-Acetylserine-13C (O-Acetyl-L-serine-13C) is the 13C-labeled O-Acetylserine (HY-101409). O-Acetylserine (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the amino acid cysteine in bacteria and plants.
    O-Acetylserine-13C
  • HY-101441R
    ST-193 (Standard) 489416-12-8 98%
    ST-193 (Standard) is the analytical standard of ST-193 (HY-101441). This product is intended for research and analytical applications. ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
    ST-193 (Standard)
  • HY-101448R
    TMI-1 (Standard) 287403-39-8 98%
    TMI-1 (Standard) is the analytical standard of TMI-1 (HY-101448). This product is intended for research and analytical applications. TMI-1 (WAY-171318) inhibits TNF converting enzyme (TACE) (IC50 of 8.4 nM), ADAM-TS-4, ADAM-17 and various MMPs with oral activity. TMI-1 significantly suppresses the secretion of TNF-α , alleviating collagen-induced arthritis in mice. TMI-1 inhibits cancer cell proliferation, induces apoptosis through a caspase-dependent pathway. TMI-1 also reverses TRPV1 upregulation and lowers the levels of inflammatory factors (TNF-α、IL-1β、IL-6) in nerve cells, protecting against paclitaxel-induced neurotoxicity. TMI-1 leads to changes in pro-atherogenic lipoprotein profiles, but does not affect the progression of early lesions.
    TMI-1 (Standard)
  • HY-101476R
    Emodepside (Standard) 155030-63-0 98%
    Emodepside (Standard) is the analytical standard of Emodepside. This product is intended for research and analytical applications. Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
    Emodepside (Standard)
  • HY-101479R
    Iclaprim (Standard) 192314-93-5
    Iclaprim (Standard) is the analytical standard of Iclaprim. This product is intended for research and analytical applications. Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
    Iclaprim (Standard)
  • HY-101479S
    Iclaprim-d6 1130072-57-9 98%
    Iclaprim-d6 (AR-100-d6) is the deuterium labeled Iclaprim. Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.
    Iclaprim-d6
  • HY-101506R
    2,4,6-Tribromophenyl caproate (Standard) 16732-09-5 98%
    2,4,6-Tribromophenyl caproate (Standard) is the analytical standard of 2,4,6-Tribromophenyl caproate (HY-101506). This product is intended for research and analytical applications. 2,4,6-Tribromophenyl caproate (2,4,6-tribromophenyl caproic acid ester) is an anti-fungal agent.
    2,4,6-Tribromophenyl caproate (Standard)
  • HY-101563R
    GSK3326595 (Standard) 1616392-22-3 98%
    GSK3326595 (Standard) is the analytical standard of GSK3326595 (HY-101563). This product is intended for research and analytical applications. GSK3326595 is a protein arginine methyltransferase 5 (PRMT5) inhibitor. GSK3326595 decreases SARS-CoV-2 infection, inhibits cancer cell proliferation and induces pro-inflammatory macrophage polarization and increases hepatic triglyceride levels without affecting atherosclerosis. GSK3326595 can be used for research of relapsed/refractory mantle cell lymphoma.
    GSK3326595 (Standard)
  • HY-101634R
    ABT-072 (Standard) 1132936-00-5 98%
    ABT-072 (Standard) is the analytical standard of ABT-072 (HY-101634). This product is intended for research and analytical applications. ABT-072 is an orally active and potent non-nucleoside HCV NS5B polymerase inhibitor (HCV GT1a EC50=1 nM; HCV GT1b EC50=0.3 nM).
    ABT-072 (Standard)
  • HY-101715R
    Panidazole (Standard) 13752-33-5 98%
    Panidazole (Standard) is the analytical standard of Panidazole (HY-101715). This product is intended for research and analytical applications. Panidazole is an amoebicide.
    Panidazole (Standard)
  • HY-101725R
    Meclonazepam (Standard) 58662-84-3 98%
    Meclonazepam (Standard) (Ro 11-3128 (Standard)) is the analytical standard of Meclonazepam (HY-101725). This product is intended for research and analytical applications. Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect. Meclonazepam is active against immature S. mansoni. Meclonazepam (30 μM) eliminates 100% of immature parasites. Meclonazepam has a anti-schistosomal effect.
    Meclonazepam (Standard)
  • HY-101795R
    Larixyl acetate (Standard) 4608-49-5
    Larixyl acetate (Standard) is the analytical standard of Larixyl acetate. This product is intended for research and analytical applications. Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction.
    Larixyl acetate (Standard)
  • HY-101865R
    KKL-10 (Standard) 952849-76-2 98%
    KKL-10 (Standard) is the analytical standard of KKL-10 (HY-101865). This product is intended for research and analytical applications. KKL-10 is a small-molecule ribosome rescue inhibitor with broad-spectrum antimicrobial activity against bacteria.
    KKL-10 (Standard)
  • HY-101866R
    KKL-35 (Standard) 865285-29-6 98%
    KKL-35 (Standard) is the analytical standard of KKL-35 (HY-101866). This product is intended for research and analytical applications. KKL-35 is a trans-translation tagging reaction inhibitor with an IC50 of 0.9 μM.
    KKL-35 (Standard)
  • HY-101867R
    AU1235 (Standard) 1338780-86-1 98%
    AU1235 (Standard) is the analytical standard of AU1235 (HY-101867). This product is intended for research and analytical applications. AU1235, an adamantyl urea, is a potent MmpL3 inhibitor. The Mycobacterium tuberculosis protein MmpL3 performs an essential role in cell wall synthesis, since it effects the transport of trehalose monomycolates across the inner membrane.
    AU1235 (Standard)
Cat. No. Product Name / Synonyms Application Reactivity