2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-110137R
    Furamidine dihydrochloride (Standard) 55368-40-6 98%
    Furamidine (dihydrochloride) (Standard) is the analytical standard of Furamidine (dihydrochloride). This product is intended for research and analytical applications. Furamidine dihydrochloride (DB75 dihydrochloride) is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine dihydrochloride is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine dihydrochloride is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine dihydrochloride is effective both with single- and double-stranded DNA substrates but is slightly stronger with the duplex DNA. Furamidine dihydrochloride is also an antiparasite agent.
    Furamidine dihydrochloride (Standard)
  • HY-111151R
    AR-9281 (Standard) 913548-29-5 98%
    AR-9281 (Standard) is the analytical standard of AR-9281. This product is intended for research and analytical applications. AR9281 (APAU) is a potent, selective and orally active soluble epoxide hydrolase (s-EH) inhibitor. AR-9281 can inhibits human sEH (HsEH) and murine sEH (MsEH) with IC50 values of 13.8 nM and 1.7 nM, respectively. AR9281 can be used for the research of inflammation, hypertension and type 2 diabetes.
    AR-9281 (Standard)
  • HY-111817A
    (Rac)-ACT-451840 1839508-99-4 98%
    (Rac)-ACT-451840 is an isomer of ACT-451840 that exhibits significant antimalarial effects. (Rac)-ACT-451840 exhibits significant antimalarial activity against P. berghei-infected mice at a dose of 20 mg/kg (ED90=13 mg/kg), and has an inhibitory effect at a dose of 300 mg/kg. The ED90 of (Rac)-ACT-451840 in the P. falciparum humanized immunodeficient mouse model is 3.7 mg/kg. (Rac)-ACT-451840 is similar to artemisinin, with a rapid onset of action but requires repeated high doses.
    (Rac)-ACT-451840
  • HY-111912R
    Tribenuron-methyl (Standard) 101200-48-0
    Tribenuron-methyl (Standard) is the analytical standard of Tribenuron-methyl. This product is intended for research and analytical applications. Tribenuron-methyl, a sulfonylurea herbicide agent, can be used as the fungicide agent. Tribenuron-methyl plays an important role in controlling the weeds and diseases in wheat field.
    Tribenuron-methyl (Standard)
  • HY-112542R
    Nemadectin (Standard) 102130-84-7
    Nemadectin (Standard) is the analytical standard of Nemadectin. This product is intended for research and analytical applications. Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity.
    Nemadectin (Standard)
  • HY-112586R
    Sulfaethoxypyridazine (Standard) 963-14-4
    Sulfaethoxypyridazine (Standard) is the analytical standard of Sulfaethoxypyridazine. This product is intended for research and analytical applications. Sulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs.
    Sulfaethoxypyridazine (Standard)
  • HY-112665R
    Virginiamycin Complex (Standard) 11006-76-1
    Virginiamycin Complex (Standard) (Streptogramin (Standard)) is the analytical standard of Virginiamycin Complex (HY-112665). This product is intended for research and analytical applications. Virginiamycin Complex (Streptogramin) is an antibiotic containing two streptogramins, virginiamycin M (VM) and virginiamycin S (VS), which are produced by S. virginiae. As a complex, these two antibiotics in Virginiamycin Complex act synergistically. The action of VM is persistent and catalytic, and it can alter the affinity of ribosomes for VS. Virginiamycin Complex irreversibly inhibits protein synthesis in bacteria and has antibacterial activity.
    Virginiamycin Complex (Standard)
  • HY-113629R
    2-Keto-D-Glucose (Standard) 1854-25-7
    Cefixime (trihydrate) (Standard) is the analytical standard of Cefixime (trihydrate). This product is intended for research and analytical applications. Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.
    2-Keto-D-Glucose (Standard)
  • HY-113764R
    N-Butanoyl-DL-homoserine lactone (Standard) 98426-48-3
    N-Butanoyl-DL-homoserine lactone (Standard) is the analytical standard of N-Butanoyl-DL-homoserine lactone. This product is intended for research and analytical applications. N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
    N-Butanoyl-DL-homoserine lactone (Standard)
  • HY-114591R
    Spiromesifen (Standard) 283594-90-1
    Spiromesifen (Standard) is the analytical standard of Spiromesifen. Spiromesifen (BSN 2060) is a broad-spectrum tetrachloro acid derivative acaricide. Spiromesifen reduces lipid biosynthesis via inhibition of acetyl-CoA carboxylase, and has no cross-resistance to any resistant mite or whitefly populations.
    Spiromesifen (Standard)
  • HY-114621B
    DB772 free base 433735-90-1 98%
    DB772 free base is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 free base also has anti-prion activity.
    DB772 free base
  • HY-115440R
    CRS3123 dihydrochloride (Standard) 1013915-99-5
    Selegiline (Standard) is the analytical standard of Selegiline. This product is intended for research and analytical applications. Selegiline (Deprenyl) is a potent, selective and irreversible inhibitor of MAO-B, with an IC50 of 51 nM. Selegiline exhibits 450-flod selectivity for MAO-B over MAO-A (IC50=23 μM). Selegiline can be used for the research of Parkinson's disease, Alzheimer's disease and major depressive disorder.
    CRS3123 dihydrochloride (Standard)
  • HY-115584B
    Lufenuron, (-)- 130841-26-8 98%
    Lufenuron, (-)- is an active isomer form of Lufenuron. Lufenuron is a lipophilic benzoyl urea insecticide and chitin synthesis inhibitor that can be used for flea and fish lice control. Lufenuron inhibits the molting of arthropods.
    Lufenuron, (-)-
  • HY-116070R
    Iodoantipyrine (Standard) 129-81-7
    Iodoantipyrine (Standard) is the analytical standard of Iodoantipyrine. This product is intended for research and analytical applications. Iodoantipyrine (4-Iodoantipyrine) is an iodinated Antipyrine (HY-B0171) with potential antiviral activity. Antipyrine (Phenazone) is an antipyretic and analgesic that also serves as a molecular probe of hepatic oxidative metabolites.
    Iodoantipyrine (Standard)
  • HY-116228A
    Cadrofloxacin (hydrochloride) 128427-55-4 98%
    Cadrofloxacin (Caderofloxacin; CS-940) hydrochloride is an orally active antibacterial agent with significant bactericidal activity against quinolone-resistant Staphylococcus aureus, Gram-positive bacteria, Gram-negative bacteria and anaerobic bacteria. Cadrofloxacin hydrochloride effectively improves systemic infection and experimental Klebsiella pneumoniae pneumonia in mice. Cadrofloxacin hydrochloride can be widely used in research related to systemic bacterial infections and bacterial pneumonia.
    Cadrofloxacin (hydrochloride)
  • HY-116433R
    Nequinate (Standard) 13997-19-8
    Nequinate (Standard) is the analytical standard of Nequinate. This product is intended for research and analytical applications. Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
    Nequinate (Standard)
  • HY-116448S
    Metaflumizone-d4 98%
    Metaflumizone-d4 is deuterium labeled Metaflumizone. Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker.
    Metaflumizone-d4
  • HY-116535B
    DL-threo-PPMP 149022-18-4 98%
    DL-threo-PPMP is an inhibitor of sphingosine synthetase in Plasmodium falciparum. DL-threo-PPMP inhibits the activity of sphingosine synthetase by mimicking the substrate sphingosine. This inhibition leads to a rapid decrease in the activity of sensitive sphingosine synthetase, selectively destroying the interconnected tubular network of TVMs in the host cell cytoplasm, and this inhibition also blocks the proliferation of Plasmodium falciparum. DL-threo-PPMP can be used for the study of Plasmodium biology and the search for new antimalarial strategies.
    DL-threo-PPMP
  • HY-116541R
    Acibenzolar-S-methyl (Standard) 135158-54-2
    Acibenzolar-S-methyl (Standard) is the analytical standard of Acibenzolar-S-methyl. This product is intended for research and analytical applications. Acibenzolar-S-methyl (ASM) is a plant resistance inducer that mimics pathogen-host interactions and leads to systemic acquired resistance in plants. Acibenzolar-S-methyl helps reduce the use of pesticides and can be used in research to prevent plant diseases.
    Acibenzolar-S-methyl (Standard)
  • HY-116568R
    Prothioconazole (Standard) 178928-70-6
    Prothioconazole (Standard) is the analytical standard of Prothioconazole. This product is intended for research and analytical applications. Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor.
    Prothioconazole (Standard)
Cat. No. Product Name / Synonyms Application Reactivity