2. Anti-infection
  3. Bacterial
  4. Cadrofloxacin (hydrochloride)

Cadrofloxacin (hydrochloride)  (Synonyms: Caderofloxacin (hydrochloride); CS-940 (hydrochloride))

Cat. No.: HY-116228A
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Cadrofloxacin (Caderofloxacin; CS-940) hydrochloride is an orally active antibacterial agent with significant bactericidal activity against quinolone-resistant Staphylococcus aureus, Gram-positive bacteria, Gram-negative bacteria and anaerobic bacteria. Cadrofloxacin hydrochloride effectively improves systemic infection and experimental Klebsiella pneumoniae pneumonia in mice. Cadrofloxacin hydrochloride can be widely used in research related to systemic bacterial infections and bacterial pneumonia.

For research use only. We do not sell to patients.

Cadrofloxacin (hydrochloride)

Cadrofloxacin (hydrochloride) Chemical Structure

CAS No. : 128427-55-4

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Cadrofloxacin (hydrochloride) Related Antibodies

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Description

Cadrofloxacin (Caderofloxacin; CS-940) hydrochloride is an orally active antibacterial agent with significant bactericidal activity against quinolone-resistant Staphylococcus aureus, Gram-positive bacteria, Gram-negative bacteria and anaerobic bacteria. Cadrofloxacin hydrochloride effectively improves systemic infection and experimental Klebsiella pneumoniae pneumonia in mice. Cadrofloxacin hydrochloride can be widely used in research related to systemic bacterial infections and bacterial pneumonia[1].

In Vitro

Cadrofloxacin hydrochloride (0.006-25 μg/mL; 18 h-48 h) exhibits broad-spectrum in vitro antibacterial activity against clinical isolates of gram-positive, gram-negative, anaerobic, Salmonella, Shigella, and Neisseria spp., with notably enhanced activity against methicillin-resistant and quinolone-resistant S. aureus (MIC90 = 12.5 μg/mL and 25 μg/mL, respectively)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cadrofloxacin (hydrochloride) Related Antibodies
In Vivo

Cadrofloxacin (hydrochloride) (0.0035-0.98 mg/mouse; p.o.; single dose; 2 hours post-infection) exhibits potent in vivo protective activity against 8 bacterial systemic infections in mice, with ED50 values ranging from 0.0035 to 0.98 mg/mouse[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ddY mice (male, ~20 g, intraperitoneally infected with bacterial strains)[1]
Dosage: 0.0035-0.98 mg/mouse
Administration: p.o.; single dose; 2 hours post-infection
Result: Achieved an ED50 of 0.016 mg/mouse against S. aureus Smith.
Achieved an ED50 of 0.18 mg/mouse against quinolone-resistant S. aureus QR-51.
Achieved an ED50 of 0.98 mg/mouse against S. pneumoniae type III.
Achieved an ED50 of 0.44 mg/mouse against S. pyogenes C-203.
Achieved an ED50 of 0.0035 mg/mouse against E. coli KC-14.
Achieved an ED50 of 0.012 mg/mouse against K. pneumoniae KC-1.
Achieved an ED50 of 0.074 mg/mouse against S. marcescens T-55.
Achieved an ED50 of 0.076 mg/mouse against P. aeruginosa E-2.
Molecular Weight

447.84

Formula

C19H21ClF3N3O4
CAS No.
SMILES

FC(F)OC1=C2N(C3CC3)C=C(C(C2=CC(F)=C1N4C[C@@H](NCC4)C)=O)C(O)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cadrofloxacin (hydrochloride) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cadrofloxacin (hydrochloride)128427-55-4CaderofloxacinCS-940CS940CS 940Bacterialgram-negative bacteriaSalmonellaEscherichia coliKlebsiella pneumoniaePseudomonas aeruginosaanaerobic bacteriaShigellaStaphylococcus aureusgram-positive bacteriaNeisseria spp.Inhibitorinhibitorinhibit

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