(Rac)-ACT-451840
(Rac)-ACT-451840 is an isomer of ACT-451840 that exhibits significant antimalarial effects. (Rac)-ACT-451840 exhibits significant antimalarial activity against P. berghei-infected mice at a dose of 20 mg/kg (ED90=13 mg/kg), and has an inhibitory effect at a dose of 300 mg/kg. The ED90 of (Rac)-ACT-451840 in the P. falciparum humanized immunodeficient mouse model is 3.7 mg/kg. (Rac)-ACT-451840 is similar to artemisinin, with a rapid onset of action but requires repeated high doses.
For research use only. We do not sell to patients.
- CAS No.: 1839508-99-4
- Formula: C47H54N6O3
- Molecular Weight:750.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Chemical Information
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CAS No. 1839508-99-4
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Molecular Weight 750.97
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Formula C47H54N6O3
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SMILES
CC(N(CC1)CCN1C(C=C2)=CC=C2CN(C(/C=C/C3=CC=C(C=C3)C(C)(C)C)=O)C(CC4=CC=CC=C4)C(N5CCN(CC5)CC6=CC=C(C=C6)C#N)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(Rac)-ACT-451840 Related Classifications
HY-111817A Related Classifications
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