2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-15232BR
    Tenofovir alafenamide hemifumarate (Standard) 1392275-56-7 98%
    Tenofovir alafenamide hemifumarate (Standard) is the analytical standard of Tenofovir alafenamide hemifumarate. This product is intended for research and analytical applications. Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
    Tenofovir alafenamide hemifumarate (Standard)
  • HY-15232S2
    Tenofovir alafenamide-d6 98%
    Tenofovir alafenamide-d6 (GS-7340-d6) is deuterium labeled Tenofovir alafenamide. Tenofovir alafenamide (GS-7340) is an investigational oral proagent of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
    Tenofovir alafenamide-d6
  • HY-15287AR
    Nelfinavir Mesylate (Standard) 159989-65-8 98%
    Nelfinavir (Mesylate) (Standard) is the analytical standard of Nelfinavir (Mesylate). This product is intended for research and analytical applications. Nelfinavir Mesylate (AG 1343 Mesylate) is a potent and orally bioavailable HIV-1 protease inhibitor (Ki=2 nM) for HIV infection. Nelfinavir Mesylate (AG 1343 Mesylate) is a broad-spectrum, anticancer agent.
    Nelfinavir Mesylate (Standard)
  • HY-153007A
    DHFR-IN-5 hydrochloride 1142407-60-0 98%
    DHFR-IN-5 hydrochloride is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a Ki value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 hydrochloride shows anti-malaria activity.
    DHFR-IN-5 hydrochloride
  • HY-15303AR
    Pritelivir mesylate (Standard) 1428333-96-3 98%
    Pritelivir (mesylate) (Standard) is the analytical standard of Pritelivir (mesylate). This product is intended for research and analytical applications. Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2.
    Pritelivir mesylate (Standard)
  • HY-15306AR
    Eltrombopag Olamine (Standard) 496775-62-3 98%
    Eltrombopag (Olamine) (Standard) is the analytical standard of Eltrombopag (Olamine). This product is intended for research and analytical applications. Eltrombopag Olamine (Eltrombopag diethanolamine salt) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag Olamine owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag Olamine can be used for the research of cardiovascular. Eltrombopag Olamine also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag Olamine can induce apoptosis in hepatocellular carcinomab (HCC) as well.
    Eltrombopag Olamine (Standard)
  • HY-15440AR
    Fostemsavir (Standard) 864953-29-7 98%
    Fostemsavir (Standard) is the analytical standard of Fostemsavir. This product is intended for research and analytical applications. Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
    Fostemsavir (Standard)
  • HY-15440AS
    Fostemsavir-d8 98%
    Fostemsavir-d8 (BMS-663068-d8) is deuterium labeled Fostemsavir. Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
    Fostemsavir-d8
  • HY-15440BR
    Fostemsavir Tris (Standard) 864953-39-9 98%
    Fostemsavir Tris (Standard) is the analytical standard of Fostemsavir Tris. This product is intended for research and analytical applications. Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl proagent of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.
    Fostemsavir Tris (Standard)
  • HY-15602S1
    Ledipasvir-d16 98%
    Ledipasvir-d16 (GS-5885-d16) is deuterium labeled Ledipasvir. Ledipasvir (GS-5885) is an inhibitor of the hepatitis C virus NS5A, with EC50s of 34 pM and 4 pM against genotype 1a and 1b replicon, respectively. Ledipasvir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.62 μM.
    Ledipasvir-d16
  • HY-156859A
    NSC309401 750522-61-3 98%
    NSC309401 is an inhibitor of E. coli DHFR (IC50: 189 nM, KD: 14.57 nM).
    NSC309401
  • HY-158824B
    Asvasiran sodium scrambled negative control 98%
    Asvasiran sodium scrambled negative control is the sequence scrambled negative control of Asvasiran sodium.
    Asvasiran sodium scrambled negative control
  • HY-158824C
    FAM labled Asvasiran sodium 98%
    FAM labled Asvasiran sodiumis a FAM labled Asvasiran sodium.
    FAM labled Asvasiran sodium
  • HY-158824D
    Cy3 labled Asvasiran sodium 98%
    Cy3 labled Asvasiran sodium is a Cy3 labled Asvasiran sodium.
    Cy3 labled Asvasiran sodium
  • HY-160198G
    Vaccine adjuvant-1 (GMP) 98%
    Vaccine adjuvant-1 GMP is Vaccine adjuvant-1 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Vaccine adjuvant-1 is an vaccine adjuvant is a vaccine adjuvant containing an oil phase, emulsifying agent and water.
    Vaccine adjuvant-1 (GMP)
  • HY-160943A
    F594-1001 hydrochloride 98%
    F594-1001 (compound 6) hydrochloride is a potent and highly selective SARS-CoV-2 Mac1-ADP-ribose inhibitor with IC50s of 8.5 μM, 68 μM and 45 μM for SARS-CoV-2 in AS, FP, and FRET assays, respectively. F594-1001 hydrochloride directly binds to SARS-CoV-2 Mac1 and exhibits a dose-dependent inhibition of Mac1 ADP-ribosylhydrolase activity.
    F594-1001 hydrochloride
  • HY-163508A
    (E)-Antibacterial agent 210 65937-49-7 98%
    (E)-Antibacterial agent 210 is the isomer of Antibacterial agent 210 (HY-163508). Antibacterial agent 210 is a Pseudomonas aeruginosa quorum sensing inhibitor (QSI). Antibacterial agent 210 inhibits the quorum sensing systems by binding with LasR and PqsR, especially PqsR.
    (E)-Antibacterial agent 210
  • HY-163529A
    (S)-HN0037 2233566-78-2 98.42%
    (S)-HN0037 is the (S)-isomer of HN0037 (HY-163529), a selective and orally active helicase-primase inhibitor that inhibits HSV replication by targeting the viral helicase-primase enzyme complex.
    (S)-HN0037
  • HY-165650A
    C16 Ganglioside GM1 (d18:1/16:0) ammonium 98%
    C16 Ganglioside GM1 (d18:1/16:0) (C16-GM1) ammonium is a member of the ganglioside family containing saturated C16:0 acyl chains. C16 Ganglioside GM1 (d18:1/16:0) ammonium serves as a functional receptor for Cholera toxin (HY-P1446) B subunit, while showing reduced efficiency in both transcytosis and retrograde pathways. C16 Ganglioside GM1 (d18:1/16:0) ammonium can be used for diarrheal diseases research.
    C16 Ganglioside GM1 (d18:1/16:0) ammonium
  • HY-166670S
    Ketoconazole carbonyl-13C 98%
    Ketoconazole carbonyl-13C (Ketoconazol-13C) is 13C labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
    Ketoconazole carbonyl-13C
Cat. No. Product Name / Synonyms Application Reactivity