2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2261
    Ipecoside 15401-60-2 98.38%
    Ipecoside is an alkaloid isolated from Psychotria.
    Ipecoside
  • HY-N2267
    (+)-Schisandrin B 82467-52-5 99.56%
    (+)-Schisandrin B is an enantiomer of Schisandrin B. Schisandrin B is an active dibenzocyclooctadiene derivative isolated from the fruit of Schisandra chinensis, has antioxidant effect on rodent liver and heart.
    (+)-Schisandrin B
  • HY-N2352
    Laurolitsine 5890-18-6 98.73%
    Laurolitsine ((+)-Norboldine) is an alkaloid isolated from the leaves of Peumus boldus Molina. Laurolitsine hydriodide shows weak anti-inflammatory activity.
    Laurolitsine
  • HY-N2359
    Chelerythrine 34316-15-9 98%
    Chelerythrine is a natural alkaloid, acts as a potent and selective Ca2+/phospholopid-dependent PKC antagonist, with an IC50 of 0.7 μM. Chelerythrine has antitumor, antidiabetic and anti-inflammatory activity. Chelerythrine inhibits the BclXL-Bak BH3 peptide binding with IC50 of 1.5 μM and displaces Bax from BclXL. Chelerythrine triggers apoptosis and autophagy.
    Chelerythrine
  • HY-N2423
    Sinigrin hydrate 64550-88-5 99.92%
    Sinigrin (Allyl-glucosinolate) hydrate is an orally active glucosinolate found in cruciferous plants. Sinigrin hydrate possesses multiple activities such as anti-cancer, antibacterial, antifungal, anti-inflammatory, antioxidant, and inhibition of fat synthesis. Sinigrin hydrate can be used in the research of tumors, inflammatory, and metabolic diseases.
    Sinigrin hydrate
  • HY-N2478
    Taraxasteryl acetate 6426-43-3 98.74%
    Taraxasteryl acetate is isolated from P. sagittalis,and has a broad spectrum of anti-inflammatory activity. Taraxasterol acetate promotes RNF31 degradation by activating autophagy. Taraxasteryl acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema. Taraxasteryl acetate can be used for the topical inflammation treatment[1][2].
    Taraxasteryl acetate
  • HY-N2490
    Dehydrotrametenolic acid 6879-05-6 99.95%
    Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects.
    Dehydrotrametenolic acid
  • HY-N2516
    Ginsenoside Rd2 83480-64-2
    Ginsenoside Rd2 is a saponin found in Panax japonicus with anti-inflammatory actions.
    Ginsenoside Rd2
  • HY-N2586
    Tenuifoliside C 139726-37-7 99.57%
    Tenuifoliside C, isolated from polygala tenuifolia willd, significantly inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
    Tenuifoliside C
  • HY-N2596
    Isoscabertopin 439923-16-7 99.0%
    Isoscabertopin is a sesquiterpene lactone isolated from Elephantopus scaber L and shows anti-tumor activities.
    Isoscabertopin
  • HY-N2714
    6-Hydroxyrubiadin 87686-86-0 99.79%
    6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases.
    6-Hydroxyrubiadin
  • HY-N2735
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene 1111897-60-9
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC50 values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus.
    7,3',4'-Trihydroxy-3-benzyl-2H-chromene
  • HY-N2843
    α-Amyrin palmitate 22255-10-3 98.0%
    α-Amyrin palmitate is isolated from Santalum album (sandalwood). α-Amyrin palmitate can be used for the study of arthritis in vivo.
    α-Amyrin palmitate
  • HY-N2883
    Salipurpin 28757-27-9 99.01%
    Salipurpin (Apigenin 5-glucoside) is a flavonoid compound isolated from the branches and leaves of Cephalotaxus fortunei, which has certain anti-inflammatory activity.
    Salipurpin
  • HY-N2913
    Ayanin 572-32-7 98.18%
    Ayanin is a bioflavonoid isolated from Psychotria serpens. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al.
    Ayanin
  • HY-N2943
    Blumeatin B 79995-67-8 99.73%
    Blumeatin B is a flavonoid and an antioxidant agent.
    Blumeatin B
  • HY-N3115
    Palbinone 139954-00-0 ≥98.0%
    Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, potently inhibits 3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46 nM. Anti-inflammatory activity.
    Palbinone
  • HY-N3163
    Obtucarbamate A 6935-99-5 99.59%
    Obtucarbamate A isolated from Disporum cantoniense has antitussive activity.
    Obtucarbamate A
  • HY-N3187
    Nimbin 5945-86-8 ≥98.0%
    Nimbin is an orally active intermediate limonoid found in Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin is promising for research of neurodegenerative diseases and viral infections.
    Nimbin
  • HY-N3260
    Methyllucidone 19956-54-8 98.0%
    Methyllucidone is a neuroprotective agent and an antioxidant that can be isolated from Lindera erythrocarpa Makino. Methyllucidone inhibits the ROS production, and activates antioxidant signaling pathways that include Nrf-2 and PI3K.
    Methyllucidone
Cat. No. Product Name / Synonyms Application Reactivity