6-Hydroxyrubiadin

Cat. No.: HY-N2714: FAQs
Data Sheet Handling Instructions

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6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases.

For research use only. We do not sell to patients.

6-Hydroxyrubiadin Chemical Structure

CAS No. : 87686-86-0

Size	Price	Stock	Quantity
1 mg	USD 210	Get quote 2 weeks 1 week	Estimated Time of Arrival: December 31
5 mg	USD 530	Get quote 2 weeks 1 week	Estimated Time of Arrival: December 31
10 mg		Get quote	Estimated Time of Arrival: December 31
25 mg		Get quote	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description	6-Hydroxyrubiadin, a natural anthraquinone, may be a potential therapeutic candidate for the treatment of inflammation and inflammatory diseases^[1].
In Vitro	6-hydroxyrubiadin suppresses lipopolysaccharide (LPS)-induced nuclear factor-kappa B activation as well as the phosphorylation of c-Jun N-terminal kinase in RAW 264.7 macrophages^[1]. 6-hydroxyrubiadin inhibited the expression of tumor necrosis factor (TNF)-a, interleukin (IL)-1b and IL-6 in phorbol myristate acetate (PMA)-primed U937 and RAW 264.7cells^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 6-Hydroxyrubiadin Related Antibodies
In Vivo	6-hydroxyrubiadin can reduce the production of pro-inflammatory cytokines and ameliorate acute lung injury (ALI) in a mouse model^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight	270.24
Formula	C₁₅H₁₀O₅
CAS No.	87686-86-0
SMILES	O=C1C2=C(C=C(O)C=C2)C(C3=CC(O)=C(C)C(O)=C13)=O
Structure Classification	Phenols Polyphenols Ketones, Aldehydes, Acids
Initial Source	Plants Rubiaceae Rubia cordifolia L.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Yanting Wu, et al. In vitro and in vivo inhibitory effects of 6-hydroxyrubiadin on lipopolysaccharide-induced inflammation. Immunopharmacol Immunotoxicol. 2017 Jun;39(3):107-116. [Content Brief]

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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6-Hydroxyrubiadin87686-86-0OthersInhibitorinhibitorinhibit

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6-Hydroxyrubiadin

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