Rubiaceae

Rubia cordifolia L. (20)
Gardenia jasminoides Ellis (16)
Uncaria rhynchophylla (Miq.) Miq. ex Havil. (14)
Morinda officinalis How (11)
Cinchona ledgeriana (Howard) Moens et Trim (7)
Cinchona succirubra Pav. ex Klotzsch (5)
Hedyotis diffusa Willd. (5)
Morinda citrifolia Linn. (5)
Coffea canephora Pierre ex Froehn. (4)
Knoxia valerianoides Thorel ex Pitard (4)
Paederia scandens (Lour.) Merr. (4)
Rubia podantha (4)
Nauclea officinalis (Pirre ex Pitard) Merr. (3)
Uncaria hirsutaHavil. (2)
Coffea arabica L. (2)
Gardenia sootepensis hutchins. (2)
Hedyotis uncinella Hook. et Arn. (2)
Neolamarckia cadamba (Roxb.) Bosser (2)
Adina rubella Hance (1)
Cinchona officinalis Linn. (1)
Damnacanthus major Sieb. et Zucc. (1)
Exostema mexicanum Gray (1)
Faramea salicifolia Presi (1)
Gardenia urvillei Montrouz. (1)
Guettarda angelica Mart. ex Müll.Arg. (1)
Haldina cordifolia (Roxb.) Ridsd. (1)
Hamelia patens Jacq. (1)
Hedyotis puberula (G. Don) Arn. (1)
Mitragyna inermis (Willd.) Kuntze (1)
Morinda lucida Benth. (1)
Morinda umbellata (1)
Mussaenda pubescens W. T. Aiton (1)
Pausinystalia johimbe (1)
Prismatomeris filamentosa Craib (1)
Psychotria forsteriana A.Gray (1)
Psychotria serpens Linn. (1)
Rubia yunnanensis Diels (1)
Rubia yunnanensis (1)
Spermadictyon suaveolens Roxb. (1)
Tarenna attenuata (Voigt) Hutchins. (1)
Uncaria tomentosa (Willd. ex Schult.) DC. (1)

Rubiaceae (137):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-17389

Genipin	6902-77-8	99.67%
Genipin ((+)-Genipin) is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. Genipin inhibits UCP2 (uncoupling protein 2) in cells. Genipin has a variety of bioactivities, including modulation on proteins, antitumor, anti-inflammation, immunosuppression, antithrombosis, and protection of hippocampal neurons. Genipin also can be used for type 2 diabetes research.

HY-D0143

Quinine	130-95-0	98.05%
Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM.

HY-N0342

Scopoletin 92-61-5 99.70%

Scopoletin is an inhibitor of acetylcholinesterase (AChE).

Scopoletin	92-61-5	99.70%
Scopoletin is an inhibitor of acetylcholinesterase (AChE).

HY-N0009

Geniposide	24512-63-8	99.89%
Geniposide is an iridoid glucoside extracted from Gardenia jasminoidesEllis fruits; exhibits a varity of biological activities such as anti-diabetic, antioxidative, antiproliferative and neuroprotective activities.

HY-B1302

Quinidine hydrochloride monohydrate 6151-40-2 99.61%

Quinidine hydrochloride monohydrate is an anti-arrythmic agent which is also a potent blocker of K⁺ channel with an IC₅₀ of 19.9 μM.

Quinidine hydrochloride monohydrate	6151-40-2	99.61%
Quinidine hydrochloride monohydrate is an anti-arrythmic agent which is also a potent blocker of K⁺ channel with an IC₅₀ of 19.9 μM.

HY-N10002

Caffeoyltryptophan	109163-69-1
Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC₅₀ of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase, linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes.

HY-N10044

3-Feruloyl-4-caffeoylquinic acid 96990-65-7

3-Feruloyl-4-caffeoylquinic acidis acaffeoyl, feruloyl quinic acidderivativeisolated fromroasted C.arabica.
HY-N11711

Pumiloside 126722-26-7

Pumiloside is a natural product that can be isolated from Nauclea officinalis. Pumiloside is a AchE inhibitor with IC₅₀ value of 118.36 μM.

3-Feruloyl-4-caffeoylquinic acid	96990-65-7
3-Feruloyl-4-caffeoylquinic acidis acaffeoyl, feruloyl quinic acidderivativeisolated fromroasted C.arabica.

Pumiloside	126722-26-7
Pumiloside is a natural product that can be isolated from Nauclea officinalis. Pumiloside is a AchE inhibitor with IC₅₀ value of 118.36 μM.

HY-B0433A

Quinine hydrochloride dihydrate	6119-47-7	≥98.0%
Quinine hydrochloride dihydrate (Qualaquin) is an orally active and can be used in anti-malarial studies. Quinine hydrochloride dihydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K_Ca5.1) channel currents evoked by voltage pulses to +100 mV with an IC₅₀ of 169 μM.

HY-Y0152

Cinchonine	118-10-5	99.56%
Cinchonine is a natural compound present in Cinchona bark with antimalarial, antitumor, anti-inflammatory, anti platelet-aggregation and anti-obesity properties. Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells.

HY-N0571

Purpurin 81-54-9 98.03%

Purpurin is a natural anthraquinone compound from Rubia cordifolia L.. Purpurin has antidepressant-like effects.

Purpurin	81-54-9	98.03%
Purpurin is a natural anthraquinone compound from Rubia cordifolia L.. Purpurin has antidepressant-like effects.

HY-N6257

Cafestol	469-83-0	99.91%
Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE₂ production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE₂ production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects.

HY-N0316

Mollugin	55481-88-4	99.48%
Mollugin is an orally active and potent NF-κB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway.

HY-N0648

Monotropein	5945-50-6	99.09%
Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model.

HY-N0563

Alizarin 72-48-0 99.17%

Alizarin is a natural dye extracted from the roots of madder plant and has been widely used as a pigment in textile fabrics and paintings.

Alizarin	72-48-0	99.17%
Alizarin is a natural dye extracted from the roots of madder plant and has been widely used as a pigment in textile fabrics and paintings.

HY-N0387

Rhynchophylline	76-66-4	99.94%
Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other research..

HY-N0766

Isorhynchophylline	6859-01-4	98.30%
Isorhynchophylline is an alkaloid compound isolated from Uncaria. It can lower blood pressure, relax blood vessels, and protect nerves from damage caused by local ischemia.

HY-N6258

Kahweol	6894-43-5	≥99.0%
Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis.

HY-B0997

Hydroquinidine	1435-55-8	99.97%
Hydroquinidine (Dihydroquinidine) is a derivative of Quinidine (an antiarrhythmic agent). Hydroquinidine prolongs the QT interval and has antiarrhythmic efficacy.

HY-N2577

1F-Fructofuranosylnystose	59432-60-9	99.97%
1F-Fructofuranosylnystose can be used in the synthesis of Fructooligosaccharides (FOSs). Fructooligosaccharides exhibit lots of beneficial effects on our health and have been used as food ingredients.

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