1. MAPK/ERK Pathway
    NF-κB
  2. p38 MAPK
    NF-κB

Scopoletin (Synonyms: Gelseminic acid; Chrysatropic acid)

Cat. No.: HY-N0342 Purity: 99.57%
Data Sheet SDS Handling Instructions

Scopoletin has important anti-inflammatory activity by inhibiting the phosphorylation of NF-κB and p38 MAPK. Scopoletin cause significant suppression of sprouting of microvessels in rat aortic explants with IC50 of 0.06 μM.

For research use only. We do not sell to patients.
Scopoletin Chemical Structure

Scopoletin Chemical Structure

CAS No. : 92-61-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 92 In-stock
50 mg USD 84 In-stock
100 mg USD 108 In-stock
200 mg USD 192 In-stock
500 mg   Get quote  
1 g   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Scopoletin has important anti-inflammatory activity by inhibiting the phosphorylation of NF-κB and p38 MAPK. Scopoletin cause significant suppression of sprouting of microvessels in rat aortic explants with IC50 of 0.06 μM. target:NF-κB, p38 [1] In vitro: Scopoletin at a dose of 1?mg/kg is able to significantly reduce cell migration and exudation to the pleural fluid (p?

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 5.2037 mL 26.0186 mL 52.0373 mL
5 mM 1.0407 mL 5.2037 mL 10.4075 mL
10 mM 0.5204 mL 2.6019 mL 5.2037 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

192.17

Formula

C₁₀H₈O₄

CAS No.

92-61-5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 32 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Scopoletin
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HY-N0342
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