2. Natural Products
  3. Disease Research Fields Plants Terpenoids
  4. Pyrolaceae Rubiaceae Inflammation/Immunology Iridoids
  5. Pyrola calliantha H. Andr. Morinda officinalis How
  6. Monotropein

Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model.

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Monotropein Chemical Structure

Monotropein Chemical Structure

CAS No. : 5945-50-6

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
 USD 66 In-stock
Solution
10 mM * 1 mL in Water USD 66 In-stock
Solid
5 mg USD 60 In-stock
10 mg USD 100 In-stock
20 mg USD 180 In-stock
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Based on 1 publication(s) in Google Scholar

Monotropein Related Antibodies

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Description

Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model[1].

Molecular Weight

390.34

Formula

C16H22O11
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

O[C@H]([C@@H](O)[C@@H]1O)[C@](O[C@@H]1CO)([H])O[C@H]2[C@@]([C@@]3(O)CO)([H])[C@@](C=C3)([H])C(C(O)=O)=CO2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 31.25 mg/mL (80.06 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5619 mL 12.8093 mL 25.6187 mL
5 mM 0.5124 mL 2.5619 mL 5.1237 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.09%

COA (258 KB) HNMR (278 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.5619 mL 12.8093 mL 25.6187 mL 64.0467 mL
5 mM 0.5124 mL 2.5619 mL 5.1237 mL 12.8093 mL
10 mM 0.2562 mL 1.2809 mL 2.5619 mL 6.4047 mL
15 mM 0.1708 mL 0.8540 mL 1.7079 mL 4.2698 mL
20 mM 0.1281 mL 0.6405 mL 1.2809 mL 3.2023 mL
25 mM 0.1025 mL 0.5124 mL 1.0247 mL 2.5619 mL
30 mM 0.0854 mL 0.4270 mL 0.8540 mL 2.1349 mL
40 mM 0.0640 mL 0.3202 mL 0.6405 mL 1.6012 mL
50 mM 0.0512 mL 0.2562 mL 0.5124 mL 1.2809 mL
60 mM 0.0427 mL 0.2135 mL 0.4270 mL 1.0674 mL
80 mM 0.0320 mL 0.1601 mL 0.3202 mL 0.8006 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monotropein5945-50-6OthersInhibitorinhibitorinhibit

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