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  4. Uncaria rhynchophylla (Miq.) Miq. ex Havil.

Uncaria rhynchophylla (Miq.) Miq. ex Havil.

Uncaria rhynchophylla (Miq.) Miq. ex Havil. (13):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0590
    Corynoxeine 630-94-4 99.59%
    Corynoxeine, isolated from the hook of Uncaria rhynchophylla, is a potent ERK1/ERK2 inhibitor of key PDGF-BB-induced vascular smooth muscle cells (VSMCs) proliferation.
    Corynoxeine
  • HY-N0387
    Rhynchophylline 76-66-4 99.64%
    Rhyncholphylline, an alkaloid isolated from Uncaria, shows potent inhibition of lipopolysaccharide (LPS)-induced NO production in rat primary microglial cells.
    Rhynchophylline
  • HY-N0901A
    Corynoxine B 17391-18-3 99.76%
    Corynoxine B is an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese); a Beclin-1-dependent autophagy inducer.
    Corynoxine B
  • HY-N0901
    Corynoxine 6877-32-3 99.58%
    Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway.
    Corynoxine
  • HY-N0766
    Isorhynchophylline 6859-01-4 99.90%
    Isorhynchophylline (IRN), an alkaloid isolated from Uncaria rhynchophylla, possesses the effects of lowered blood pressure, vasodilatation and protection against ischemia-induced neuronal damage.
    Isorhynchophylline
  • HY-N2411
    Geissoschizine methyl ether 60314-89-8 ≥98.0%
    Geissoschizine methyl ether, a major indole alkaloid found in Uncaria hook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent 5-HT1A receptor agonist.
    Geissoschizine methyl ether
  • HY-N2193
    Hirsutine 7729-23-9 ≥99.0%
    Hirsutine, an indole alkaloid of Uncaria rhynchophylla, exhibits anti-cancer activity. Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.
    Hirsutine
  • HY-N6946
    Mitraphylline 509-80-8 99.71%
    Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils.
    Mitraphylline
  • HY-N0775
    Isocorynoxeine 51014-29-0 99.95%
    Isocorynoxeine, an isorhynchophylline-related alkaloid, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM.
    Isocorynoxeine
  • HY-N2197
    Hirsuteine 35467-43-7 ≥99.0%
    Hirsuteine is an indole alkaloid extracted from Uncaria genus. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes.
    Hirsuteine
  • HY-N4157
    Isopteropodine 5171-37-9 98.66%
    Isopteropodine is heteroyohimbine-type oxindole alkaloid components of Uncaria tomentosa (Willd.) DC. Isopteropodine acts as positive modulators of muscarinic M1 and 5-HT2 receptors.
    Isopteropodine
  • HY-N1089
    Vincosamide 23141-27-7
    Vincosamide, an alkaloid from Psychotria leiocarpa extract, inhibits the acetylcholinesterase (AChE) activity with anti-inflammatory activity.
    Vincosamide
  • HY-N0901B
    Corynoxine hydrochloride
    Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway.
    Corynoxine hydrochloride