1. Alkaloids
  2. Mitraphylline

Mitraphylline 

Cat. No.: HY-N6946 Purity: 99.71%
Handling Instructions

Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils.

For research use only. We do not sell to patients.

Mitraphylline Chemical Structure

Mitraphylline Chemical Structure

CAS No. : 509-80-8

Size Price Stock Quantity
5 mg USD 316 In-stock
Estimated Time of Arrival: December 31
10 mg USD 538 In-stock
Estimated Time of Arrival: December 31
20 mg USD 914 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].

Molecular Weight

368.43

Formula

C₂₁H₂₄N₂O₄

CAS No.

509-80-8

SMILES

O=C1NC2=C([[email protected]@]13CCN4C[[email protected]@]5([[email protected]@H](OC=C([[email protected]]5(C[[email protected]]43[H])[H])C(OC)=O)C)[H])C=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 6.76 mg/mL (18.35 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7142 mL 13.5711 mL 27.1422 mL
5 mM 0.5428 mL 2.7142 mL 5.4284 mL
10 mM 0.2714 mL 1.3571 mL 2.7142 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

MitraphyllineOthersUncariatomentosaInhibitorinhibitorinhibit

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Mitraphylline
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HY-N6946
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