Dehydrotrametenolic acid
Based on 1 Customer Validation
Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 6879-05-6
- Formula: C31H48O3
- Molecular Weight:468.71
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Caspase Isoforms
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Biological Activity
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Caspase-3 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
6.3 μM
Compound: 12
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Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay
Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay
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[PMID: 27808511] |
| HL-60 | IC50 |
6 μM
Compound: 12
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Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
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[PMID: 27808511] |
| K562 | IC50 |
25.6 μM
Compound: 12
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Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
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[PMID: 27808511] |
| MCF7 | IC50 |
>100 μM
Compound: 19
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Cytotoxicity against human MCF7 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human MCF7 cells incubated for 24 hrs by MTT assay
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[PMID: 31891260] |
| MOLT-4 | IC50 |
14.3 μM
Compound: 12
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Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay
Antiproliferative activity against human MOLT4 cells after 72 hrs by MTT assay
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[PMID: 27808511] |
| Neutrophil | IC50 |
77.5 μM
Compound: 12
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Inhibition of fMLP-induced superoxide production in human neutrophils
Inhibition of fMLP-induced superoxide production in human neutrophils
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[PMID: 17559265] |
| SW480 | IC50 |
>100 μM
Compound: 19
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Cytotoxicity against human SW480 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human SW480 cells incubated for 24 hrs by MTT assay
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[PMID: 31891260] |
| U-251 | IC50 |
>100 μM
Compound: 19
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Cytotoxicity against human U251 cells incubated for 24 hrs by MTT assay
Cytotoxicity against human U251 cells incubated for 24 hrs by MTT assay
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[PMID: 31891260] |
Chemical Information
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CAS No. 6879-05-6
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Appearance Solid
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Molecular Weight 468.71
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Formula C31H48O3
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Color White to off-white
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SMILES
C[C@]12C3=CC[C@](C(C)([C@@H](O)CC4)C)([H])[C@@]4(C)C3=CC[C@@]1([C@]([C@H](C(O)=O)CCC(C(C)C)=C)([H])CC2)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 1 mg/mL (2.13 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1335 mL | 10.6676 mL | 21.3352 mL | 53.3379 mL |
Dehydrotrametenolic acid Related Classifications
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