2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19589
    JTS-653 942614-99-5 98%
    JTS-653 is a highly potent and selective transient receptor potential vanilloid 1 (TRPV1) antagonist in vitro and in vivo. JTS-653 attenuates chronic pain refractory to non-steroidal anti-inflammatory agents.
    JTS-653
  • HY-19591
    Fluazacort 19888-56-3 98%
    Fluazacort (L-6400), oxazolino corticosteroid, is a Glucocorticoid Receptor (GR) modulator. Fluazacort can be used for the research of inflammation, immunology and metabolic disease.
    Fluazacort
  • HY-19596
    Fenprinast 75184-94-0 98%
    Fenprinast is a cromotyn-like bronchodilator used for the research of allergy and exercise-induced asthma. Fenprinast has oral bioactivity.
    Fenprinast
  • HY-19604
    SQ 26490 59497-39-1 98%
    SQ 26490 is an active corticoid, moderate-potency edema formation inhibitor. SQ 26490 inhibits edema formation in rats.
    SQ 26490
  • HY-19606
    Cytogenin 132971-59-6 98%
    Cytogenin (Antibiotic MI 43-37F11) is an orally active antineoplastic antibiotic. Cytogenin regulates the inflammatory cytokine, reduces the levels of iNOS, NO and IL-6 in mouse macrophages, and exhibits antidiabetic efficacy in mice. Cytogenin inhibits growth of Ehrlich ascites tumor in mouse model.
    Cytogenin
  • HY-19665
    Lanepitant 170566-84-4 98%
    Lanepitant (LY303870) is a selective neurokinin-1 (NK-1) receptor antagonist. Lanepitant blocks neurogenic inflammation and pain transmission by preventing the binding of substance P to NK-1 receptors on both neuronal and non-neuronal tissues. Lanepitant can be used to study osteoarthritis.
    Lanepitant
  • HY-19680
    Prinomide tromethamine 109636-76-2 98%
    Prinomide tromethamine is an orally available nonsteroidal anti-inflammatory agent. Prinomide tromethamine can be used to study inflammation, such as rheumatoid arthritis.
    Prinomide tromethamine
  • HY-19704
    Pegcantratinib 1233363-33-1 98%
    Pegcantratinib (CT327) is a potent and selective TRKA antagonist with activity against TRKB and TRKC. Pegcantratinib can be used for research of CYLD cutaneous syndrome (CCS) and inflammatory dermatoses, such as psoriasis and concomitant pruritus.
    Pegcantratinib
  • HY-19755
    S-5751 209268-36-0 98%
    S-5751 is an orally active prostaglandin DP receptor antagonist. S-5751 inhibits cAMP generation in platelet-rich plasma induced by PGD2 with IC50 0.12 μM. S-5751 has anti-inflammatory activity. S-5751 can be used in asthma research.
    S-5751
  • HY-19854
    TRO-40303 949080-24-4 98%
    TRO-40303 is a cell protective compound targeting mitochondrial TSPO. TRO-40303 significantly improves the survival rate of liver cells and reduces cell death by reducing oxidative stress. TRO-40303 is commonly used in the study of hepatitis.
    TRO-40303
  • HY-19860
    BAL-19403 905702-47-8 98%
    BAL-19403 is a macrolide antibiotic. BAL-19403 exhibits excellent activity against Propionibacterium acnes, particularly effective against erythromycin and clindamycin resistant strains. BAL-19403’s main functions are antibacterial and anti-inflammatory activity. BAL-19403 can be used for research on acne.
    BAL-19403
  • HY-19865
    Azeloprazole sodium 955095-47-3 98%
    Azeloprazole sodium is a potent proton pump inhibitor (PPI). Azeloprazole sodium can be used for gastroesophageal reflux disease (GERD) research.
    Azeloprazole sodium
  • HY-19871
    AZD-3199 925243-19-2 98%
    AZD-3199 is an ultra-long-acting beta2 agonist with potential activity against asthma and chronic obstructive pulmonary disease.
    AZD-3199
  • HY-19911
    Pefcalcitol 381212-03-9 98%
    Pefcalcitol is a new antipsoriatic anteagent candidates having 16-en-22-oxa-vitamin D3 structures.
    Pefcalcitol
  • HY-23909
    7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid 89560-01-0 98%
    7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a phospholipase inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A2 (PLA2) (IC50 = 16 µM) and snake venom PLA2 (IC50 = 14 µM).
    7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid
  • HY-29468
    LCB-2183 133914-85-9 98%
    LCB-2183 is an orally active antiallergic agent. LCB-2183 can inhibit tracheal hyperreactivity and pulmonary inflammation in mouse airways.
    LCB-2183
  • HY-32347
    Tisocalcitate 156965-06-9 98%
    Tisocalcitate is a Vitamin D analogue, can be used for plaque type psoriasis research.
    Tisocalcitate
  • HY-45588
    Geranylamine 6246-48-6 98%
    Geranylamine is an acyclic monoterpene amine that serves as a drug intermediate for the synthesis of a series of TRP channel modulators and antibacterial agents.
    Geranylamine
  • HY-48869
    PI3K-IN-46 304645-61-2 98.0%
    PI3K-IN-46 (Intermediate 4) is an intermediate in the synthesis of PI3K inhibitor (2-imino-azolinone-vinyl fused-benzene derivative) that can be used for the research of autoimmune disorders, cardiovascular diseases, and neurodegenerative diseases.
    PI3K-IN-46
  • HY-50892
    (Rac)-Roscovitine 186692-44-4 98%
    (Rac)-Roscovitine ((Rac)-Seliciclib) is a selective cyclin-dependent kinases (CDKs) inhibitor. (Rac)-Roscovitine binds to the active sites of CDKs competitively with ATP, inhibiting the phosphorylation activity of CDKs. (Rac)-Roscovitine induces apoptosis in cancer cells. (Rac)-Roscovitine is promising for research of cancers or other diseases associated with CDK dysregulation, such as neurodegenerative diseases, cardiac disorders, viral and protozoan infections, glomerulonephritis, and chronic inflammation.
    (Rac)-Roscovitine
Cat. No. Product Name / Synonyms Application Reactivity