7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid
7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA), a phospholipase inhibitor, is a non-metabolizable analog of arachidonic or eicosadienoic acid. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) inhibits P388D1 cell phospholipase A2 (PLA2) (IC50 = 16 µM) and snake venom PLA2 (IC50 = 14 µM).
For research use only. We do not sell to patients.
- CAS No.: 89560-01-0
- Formula: C22H40O2
- Molecular Weight:336.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Phospholipase Isoforms
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Biological Activity
7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA, 5 μM) has a significant effect on the βA(25-35)-stimulated response. 7,7-Dimethyl-(5Z,8Z)-eicosadienoic acid (DEDA) reduces the formation of ROS[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 89560-01-0
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Molecular Weight 336.55
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Formula C22H40O2
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SMILES
CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(O)=O
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Synonyms
DEDA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)