2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N17783A
    Sanleng acid 163860-24-0
    Sanleng acid is an unsaturated fatty acid compound that can be isolated from the hexane extract of Magnolia sieboldii (MsHE). MsHE can inhibit the expression of inflammatory mediators (such as COX-2) and pro-inflammatory cytokines (such as TNF-α, IL-1β), and increase the expression of tight junction proteins (claudin-4, claudin-5) to protect epithelial cell barrier function, thus exerting anti-inflammatory activity. Related compounds may be used in research related to reflux esophagitis (RE).
    Sanleng acid
  • HY-N18117A
    23-Hydroxyohchininolide 1429747-10-3 98%
    23-Hydroxyohchininolide is a limonoid found in the leaves of Melia azedarach L.. 23-Hydroxyohchininolide inhibits LPS (HY-D1056)-induced NO production and exerts cytotoxic activity against human leukemia and stomach cancer cells. 23-Hydroxyohchininolide inhibits TPA (HY-18739)-induced Epstein-Barr virus early antigen activation. 23-Hydroxyohchininolide can be used for the research of cancer, infection and inflammatory disease.
    23-Hydroxyohchininolide
  • HY-N2021AR
    Phosphoramidon Disodium (Standard) 164204-38-0
    Indole-3-butyric acid (Standard) is the analytical standard of Indole-3-butyric acid. This product is intended for research and analytical applications. Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process.
    Phosphoramidon Disodium (Standard)
  • HY-N6070AR
    Ricinoleic acid (Standard) 141-22-0
    Ricinoleic acid (Standard) is the analytical standard of Ricinoleic acid. This product is intended for research and analytical applications. Ricinoleic acid, a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties.
    Ricinoleic acid (Standard)
  • HY-N6710S1
    α-Zearalenol-13C18
    α-Zearalenol-13C18 is the 13C-labeled α-Zearalenol. α-Zearalenol is a Mycotoxin with high affinity for the estrogen receptors (ER). α-Zearalenol is the derivative of zearalenone (ZEN), causes reproductive disorders in animals, due to its xenoestrogenic effects.
    α-Zearalenol-13C18
  • HY-N6937S1
    (R,R)-Secoisolariciresinol diglucoside-d6 98%
    (R,R)-Secoisolariciresinol diglucoside-d6 is deuterated labeled (R,R)-Secoisolariciresinol diglucoside (HY-N6937). (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells.
    (R,R)-Secoisolariciresinol diglucoside-d6
  • HY-N7106S2
    Dimethyl phthalate-13C6,d4 98%
    Dimethyl phthalate-13C6,d4 (DMP-13C6,d4) is the deuterium labeled and 13C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats.
    Dimethyl phthalate-13C6,d4
  • HY-N7106S3
    Dimethyl phthalate-13C6 98%
    Dimethyl phthalate-13C6 (DMP-13C6) is the 13C-labeled Dimethyl phthalate (HY-N7106). Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats.
    Dimethyl phthalate-13C6
  • HY-N7123S1
    Sulfacetamide-13C6 98%
    Sulfacetamide-13C6 (Sulphacetamide13C6) is the 13C6 labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities.
    Sulfacetamide-13C6
  • HY-NP0194B
    C1q Protein (rabbit) 98%
    C1q Protein (rabbit) is a complement protein and is a recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. C1q Protein (rabbit) binds various ligands derived from self, non-self, and altered self and modulate the functions of immune
    and non-immune cells. C1q Protein (rabbit) can be used for the research of mutiple disease.
    C1q Protein (rabbit)
  • HY-NP0196A
    Mouse Immunoglobulin G1
    Mouse Immunoglobulin G1 is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA.
    Mouse Immunoglobulin G1
  • HY-NP0196B
    Mouse Immunoglobulin G2a
    Mouse Immunoglobulin G2a is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA.
    Mouse Immunoglobulin G2a
  • HY-NP0196C
    Mouse Immunoglobulin G2b
    Mouse Immunoglobulin G2b is a mouse serum immunoglobulin that can be used in immunolabeling and coating protein in a variety of immunoassays including ELISA.
    Mouse Immunoglobulin G2b
  • HY-NP0196D
    Mouse IgG Fc fragment
    Mouse IgG Fc fragment is a crystallizable fragment (Fc) of mouse immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Mouse IgG Fc fragment
  • HY-NP0196E
    Mouse IgG Fab fragment
    Mouse IgG Fab fragment is a fragment of antigen (Fab) of mouse immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Mouse IgG Fab fragment
  • HY-NP0197A
    Goat IgG Fc fragment
    Goat IgG Fc fragment is a crystallizable fragment (Fc) of goat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Goat IgG Fc fragment
  • HY-NP0197B
    Goat IgG Fab fragment
    Goat IgG Fab fragment is a fragment of antigen (Fab) of goat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Goat IgG Fab fragment
  • HY-NP0198A
    Rabbit IgG Fc fragment
    Rabbit IgG Fc fragment is a crystallizable fragment (Fc) of rabbit immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Rabbit IgG Fc fragment
  • HY-NP0198B
    Rabbit IgG Fab fragment
    Rabbit IgG Fab fragment is a fragment of antigen (Fab) of rabbit immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Rabbit IgG Fab fragment
  • HY-NP0240A
    Bovine CB9.7 of type II collagen
    Bovine CB9.7 of type II collagen (Bovine cyanogen bromide digested peptide 9.7) is a cyanobromide digested peptide (CB-peptide) fragment of type II collagen, which can be used to study B cell and T cell epitopes of type II collagen. This product is pepsin-free, making it ideal for studying T cell epitope specificity through proliferation assays. Bovine CB9.7 of type II collagen can also be used as an antigen for analyzing antibody epitope specificity via ELISA.
    Bovine CB9.7 of type II collagen
Cat. No. Product Name / Synonyms Application Reactivity