2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2597R
    Prunetin (Standard) 552-59-0 98%
    Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor.
    Prunetin (Standard)
  • HY-N2605R
    Camelliaside B (Standard) 131573-90-5
    Camelliaside B (Standard) is the analytical standard of Camelliaside B. This product is intended for research and analytical applications. Camelliaside B is a flavonoid from the methanol extract of tea (Camellia oleifera) seed pomace.
    Camelliaside B (Standard)
  • HY-N2609R
    7,4'-Dihydroxyflavone (Standard) 2196-14-7 98%
    7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM.
    7,4'-Dihydroxyflavone (Standard)
  • HY-N2616R
    Vomicine (Standard) 125-15-5
    Vomicine (Standard) is the analytical standard of Vomicine. This product is intended for research and analytical applications. Vomicine modulates cGAS-STING-TBK1 signaling pathway, and exhibits anti-inflammatory activity. Vomicine is an alkaloid that can be isolated from Strychnos nux-vomica seeds.
    Vomicine (Standard)
  • HY-N2715A
    (2R)-6-Methoxynaringenin 1212075-61-0 98%
    (2R)-6-Methoxynaringenin is the R isomer of 6-Methoxynaringenin (HY-N2715). 6-Methoxynaringenin is a flavonoid, that inhibits NO production with an IC50 of 25.8 μM.
    (2R)-6-Methoxynaringenin
  • HY-N2897R
    Dihydrokaempferol (Standard) 480-20-6
    Dihydrokaempferol (Standard) is the analytical standard of Dihydrokaempferol. This product is intended for research and analytical applications. Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic agents.
    Dihydrokaempferol (Standard)
  • HY-N3006R
    Sakuranetin (Standard) 2957-21-3 98%
    Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury.
    Sakuranetin (Standard)
  • HY-N3010R
    Salviaflaside (Standard) 178895-25-5
    Salviaflaside (Standard) is the analytical standard of Salviaflaside. This product is intended for research and analytical applications. Salviaflaside is a main bioactive component of Spica Prunellae.
    Salviaflaside (Standard)
  • HY-N3011R
    Iridin (Standard) 491-74-7
    Iridin (Standard) is the analytical standard of Iridin. This product is intended for research and analytical applications. Iridin is an orally active natural isoflavone. Iridin inhibits the PI3K/AKT and PKM2 signaling pathways, and downregulates the JAK/STAT and NF-κB pathways. Iridin induces Fas-mediated extrinsic apoptosis, G2/M cell cycle arrest, and inhibits cell proliferation. Iridin reduces inflammation, inhibits ROS production, suppresses glycolysis, and also exhibits antioxidant and antidiabetic activities. Iridin can be used in research related to gastric cancer and acute lung injury.
    Iridin (Standard)
  • HY-N3017R
    Artemitin (Standard) 479-90-3 98%
    Artemitin (Standard) is the analytical standard of Artemitin. This product is intended for research and analytical applications. Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity.
    Artemitin (Standard)
  • HY-N3029R
    Noreugenin (Standard) 1013-69-0 98%
    Noreugenin (Standard) is the analytical standard of Noreugenin. This product is intended for research and analytical applications. Noreugenin is a phenolic compound found in Calea uniflora Less. Noreugenin inhibits myeloperoxidase activity and reduces levels of proinflammatory cytokines IL-1β and IL-17A levels in LPS (HY-D1056)-induced murine pleurisy model. Noreugenin reduces apoptosis and necrosis. Noreugenin reduces lipid peroxidation, and antioxidant enzyme (CAT, SOD, GST) activity. Noreugenin exhibits anti-inflammatory and antioxidant effects. Noreugenin can be used for the research of inflammatory conditions, such as pleurisy.
    Noreugenin (Standard)
  • HY-N3031R
    Grosvenorine (Standard) 156980-60-8
    Grosvenorine (Standard) is the analytical standard of Grosvenorine. This product is intended for research and analytical applications. Grosvenorine is an orally active flavonoid glycoside found in S. grosvenorii. Grosvenorine exhibits antibacterial, antioxidant and antiinflammation activities. Grosvenorine can induce apoptosis and increases anti-apoptotic Bcl-2 protein expression and reduces pro-apoptotic P53 protein expression in gastric tissues. Grosvenorine enhances mucin/glycoprotein secretion, regulates gastric pH, and reduces gastric lesion incidence.Grosvenorine increases glutathione peroxidase, catalase, and SOD levels, reduces lipid peroxidation (MDA), and lowers TNF-α and IL-6 levels. Grosvenorine can be used for the researches of bacterial infection and Gastric ulcer.
    Grosvenorine (Standard)
  • HY-N3037R
    3-O-Acetyl-α-boswellic acid (Standard) 89913-60-0
    3-O-Acetyl-α-boswellic acid (Standard) is the analytical standard of 3-O-Acetyl-α-boswellic acid. This product is intended for research and analytical applications. 3-O-Acetyl-α-boswellic acid suppresses T cell function.
    3-O-Acetyl-α-boswellic acid (Standard)
  • HY-N3074R
    Hexahydrofarnesyl acetone (Standard) 502-69-2
    alpha-Bisabolol (Standard) is the analytical standard of alpha-Bisabolol. This product is intended for research and analytical applications. alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities.
    Hexahydrofarnesyl acetone (Standard)
  • HY-N4094R
    Morellic acid (Standard) 5304-71-2
    Morellic acid (Standard) is the analytical standard of Morellic acid. This product is intended for research and analytical applications. Morellic acid is isolated from Garcinia Morella with an antiangiogenic activity.
    Morellic acid (Standard)
  • HY-N4095R
    Brevifolincarboxylic acid (Standard) 18490-95-4
    Brevifolincarboxylic acid (Standard) is the analytical standard of Brevifolincarboxylic acid (HY-N4095). This product is intended for research and analytical applications. Brevifolincarboxylic acid is a phenolic compound. Brevifolincarboxylic acid can be isolated from Duchesnea chrysantha. Brevifolincarboxylic acid inhibits α-glucosidase with an IC50 value of 323.46 μM. Brevifolincarboxylic acid has an inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarbacid scavenges ROS. Brevifolincarbacid restores the glucose uptake activity of myotubes. Brevifolincarboxylic acid has antitumor activity against lung and gastric cancer. Brevifolincarbacid can be used in the study of diabetes and inflammatory diseases.
    Brevifolincarboxylic acid (Standard)
  • HY-N4099R
    Luteolin-3-O-beta-D-glucuronide (Standard) 53527-42-7
    Luteolin-3-O-beta-D-glucuronide (Standard) is the analytical standard of Luteolin-3-O-beta-D-glucuronide (HY-N4099). This product is intended for research and analytical applications. Luteolin-3-O-beta-D-glucuronide, a glucuronide derivative of Luteolin (HY-N0162), is found in the leaves of Rosmarinus officinalis L. Luteolin-3-O-beta-D-glucuronide inhibits nitrite production in macrophages and binds strongly to FYN kinase.
    Luteolin-3-O-beta-D-glucuronide (Standard)
  • HY-N4107R
    Phyllanthin (Standard) 10351-88-9
    Phyllanthin (Standard) is the analytical standard of Phyllanthin. This product is intended for research and analytical applications. Phyllanthin is an effective oral anticancer agent. Phyllanthin inhibits MOLT-4 cell viability, increases apoptosis, inhibits cell migration and invasion. Phyllanthin exerts anti-fibrotic effects by down-regulating TGF signaling pathway via ALK5 and Smad2/3. Phyllanthin also has anti-inflammatory and antibacterial properties .
    Phyllanthin (Standard)
  • HY-N4111R
    Wushanicaritin (Standard) 521-45-9 98%
    Wushanicaritin exhibits significant antioxidant activity (IC50=35.3 μM) in DPPH radical scavenging activity tests. Antitumor effects and anti-inflammatory property.
    Wushanicaritin (Standard)
  • HY-N4122R
    Neodiosmin (Standard) 38665-01-9
    Neodiosmin (Standard) is the analytical standard of Neodiosmin. This product is intended for research and analytical applications. Neodiosmin is a flavone glycoside isolated from the leaves of Citrus aurantium.
    Neodiosmin (Standard)
Cat. No. Product Name / Synonyms Application Reactivity