2. Others

Others

Others

Related Products

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There are a number of inhibitors, agonists, and antagonists which we cannot make precise classification because the research area is still unknown.

Others Related Products (73860):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-14835
    Burapitant 537034-22-3 98%
    Burapitant (SSR240600) is a compound that modulates cholinergic transmission and regulates acetylcholine release in the limbic/prefrontal region of the rat striatum, with its effects being influenced by the interaction of 5-HT? and 5-HT? receptors.
    Burapitant
  • HY-14849
    PTZ601 426253-04-5 98%
    PTZ601 (SMP 601) is an antibiotic, which inhibits the gram-positive bacteria, including the Vancomycin (HY-B0671)-resistant Enterococcus faecium (VREF) and Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). PTZ601 exhibits antimicrobial activity in infected mouse models.
    PTZ601
  • HY-14863
    Lunacalcipol 250384-82-8 98%
    Lunacalcipol (CTA-018), as a vitamin D analogue, has a dual role in the pathogenesis of Chronic Kidney Disease (CKD), as an agonist of vitamin D receptor and an antagonist of cytochrome P450 enzyme 24-hydroxylase. Lunacalcipol binds to VDR and regulates transcriptional activity of VDR by influencing ligand binding affinity, ligand-dependent coactivator recruitment or inhibitory factor dissociation, efficiency of ligand entry into target cells, tissue specificity and different metabolism of ligand. Lunacalcipol can be used in the study of CKD, especially Secondary Hyperparathyroidism (sHPT).
    Lunacalcipol
  • HY-15350
    Trovirdine hydrochloride 148311-89-1 98%
    Trovirdine hydrochloride, a phenethylthiazolylthiourea (PETT) derivative, is an HIV reverse transcriptase (RT) non-nucleoside inhibitor (NNI). A novel computer model of the RT/NNI binding pocket revealed spatial gaps around Trovirdine hydrochloride's pyridyl ring. Docking studies suggested that replacing this planar ring with a nonplanar piperidinyl or piperazinyl ring could better occupy the binding pocket, enhancing anti-HIV activity. Synthesized heterocyclic compounds based on this modification demonstrated greater potency than Trovirdine hydrochloride, effectively inhibiting HIV replication at nanomolar concentrations without cytotoxicity in infected peripheral blood mononuclear cells.
    Trovirdine hydrochloride
  • HY-15410
    Gacyclidine 68134-81-6 98%
    Gacyclidine, a non competitive N-methyl-D-aspartate (NMDA) antagonist, can be used in the study of spinal cord injuries.
    Gacyclidine
  • HY-15923
    MAOS 82692-97-5 99.98%
    MAOS is a modified Trinder’s reagent that can be used as a chromogenic probe for the determination of H2O2. MAOS is strongly dependent on the pH of the reaction medium.
    MAOS
  • HY-16121
    CAA-0225 244072-26-2 98%
    CAA-0225 is a tissue protease L inhibitor that inhibits rat liver tissue protease L with a IC50 value of 1.9 nM. CAA-0225 can participate in the degradation of autophagosome membrane markers LC3-II and GABARAP (HY-P72639), improve cardiac function in mice with reperfusion injury, and kill and eliminate Trypanosoma brucei parasites[1][2][3].
    CAA-0225
  • HY-16387
    PF 00337210 854514-88-8 98%
    PF-00337210 is a potent and selective inhibitor of VEGFRs, designed for treating age-related macular degeneration via intravitreal injection. The formulation strategy focused on developing an ophthalmic solution that would precipitate upon injection into the vitreous, ensuring sustained drug delivery. Challenges included maintaining low dosing volumes, selecting safe excipients for intravitreal use, and addressing the drug's unique physicochemical properties. The final formulation, an isotonic solution in a citrate-buffered vehicle with NaCl, demonstrated stability, potency, and recovery through intravitreal dosing syringes. It formed a depot upon injection into vitreous humor, representing a novel nonpolymeric in situ-forming depot formulation for intravitreal drug delivery.
    PF 00337210
  • HY-16506
    Trimethaphan camsylate 68-91-7 98%
    Trimethaphan camsylate is an arterial blood pressure lowering agent that has been shown to reduce pulmonary venous pressure in experimental pulmonary edema.
    Trimethaphan camsylate
  • HY-17483
    Oxametacin 27035-30-9 98%
    Oxametacin is an active compound.
    Oxametacin
  • HY-17562
    2-Amino-5-bromo-4-methylpyridine 98198-48-2 ≥98.0%
    2-Amino-5-bromo-4-methylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    2-Amino-5-bromo-4-methylpyridine
  • HY-18005
    4-Aza-Oleanolic acid methyl ester 557766-15-1 98%
    4-Aza-Oleanolic acid methyl ester is a triterpenic derivative.
    4-Aza-Oleanolic acid methyl ester
  • HY-18037
    AMG-7980 947192-73-6 98%
    AMG-7980 exhibits high affinity to phosphodiesterase 10A (PDE10A), with a KD of 0.94 nM. AMG-7980 can be used as a tracer of PDE10A, when labeled with radioactive isotope.
    AMG-7980
  • HY-18284
    AS1938909 1243155-40-9 98%
    AS1938909 is a compound that inhibits SHIP2 activity. It can selectively inhibit SHIP2, increase Akt phosphorylation, and regulate glucose metabolism. Its effect is related to upregulating GLUT1 gene expression.
    AS1938909
  • HY-18500
    (βS)-β-Hydroxy-L-histidine hydrochloride 220195-81-3 98%
    (βS)-β-Hydroxy-L-histidine hydrochloride is a stereoisomer of β-hydroxyhistidine.
    (βS)-β-Hydroxy-L-histidine hydrochloride
  • HY-18510
    IRE1α kinase-IN-7 1414938-22-9 98%
    IRE1α kinase-IN-7 (compound 4) is an IRE1α kinase inhibitor. IRE1α kinase-IN-7 can be used for research of endoplasmic reticulum stress-related diseases.
    IRE1α kinase-IN-7
  • HY-18573
    Naxillin 301176-96-5 98%
    Naxillin is a non-auxin-like molecule, which can promote the lateral root branching in the basal meristem of the root, through the conversion of the auxin precursor indole-3-butyric acid (IBA) to the active auxin indole-3-acetic acid (IAA).
    Naxillin
  • HY-18651
    (E/Z)-Rigosertib sodium 1225497-78-8 98%
    Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    (E/Z)-Rigosertib sodium
  • HY-19022
    BW A256C 98410-36-7 98%
    Palatrigine is a compound with angiotensin-converting enzyme inhibitory and beta-adrenergic receptor blocking properties.
    BW A256C
  • HY-19040
    Ro 16-8714 90505-66-1 98%
    Ro 16-8714 is an active compound.
    Ro 16-8714