2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14097
    Pyloricidin A2
    		Inhibitor
    Pyloricidin A2 is an antibiotic against Helicobacter pylori found in Bacillus sp. HC-70. Pyloricidin A2 has strong anti-Helicobacter pylori activity. Pyloricidin A2 has no activity against other bacteria and yeast.
    Pyloricidin A2
  • HY-N14833
    Naphthoquinomycin B
    		Inhibitor
    Naphthoquinomycin B is an Ansa antibiotic with anti-Gram-positive bacteria and fungi activity, and can inhibit the synthesis of E. coli fatty acids.
    Naphthoquinomycin B
  • HY-N14700
    3-O-Demethylmonensin A
    		Inhibitor
    3-O-Demethylmonensin A is a polyether antibiotic found in Streptomyces cinnamonensis LO-63.
    3-O-Demethylmonensin A
  • HY-N5201
    4"-Demethylgentamicin C1
    		Inhibitor
    4"-Demethylgentamicin C1 has anti-Gram-positive and negative bacteria activity.
    4
  • HY-180273
    Antibacterial agent 309
    		Inhibitor
    Antibacterial agent 309 (Compound C9) is an antibacterial agent, substrate of AcrB efflux pump. Antibacterial agent 309 promotes FtsZ polymerization. Antibacterial agent 309 demonstrates antibacterial activity against Erythromycin (HY-B0220)-resistant S. pyogenes 2 (MIC = 0.25 μg/mL), Penicillin-resistant S. aureus CI (MIC = 0.125 μg/mL), Penicillin-resistant S. epidermidis (MIC = 2 μg/mL). Antibacterial agent 309 exhibits weak antibacterial activity against the wild-type E. coli BW25113 MIC = 256 μg/mL).
    Antibacterial agent 309
  • HY-175539
    DNA gyrase/Topo IV-IN-2
    		Inhibitor
    DNA gyrase/Topo IV-IN-2 (Compound AK19) is an antibacterial agent with IC50 values of 0.783 μM and 7.136 μM against E. coli DNA gyrase and topoisomerase IV, respectively. DNA gyrase/Topo IV-IN-2 exhibits broad-spectrum antibacterial efficacy against both Gram-positive and Gram-negative pathogens. DNA gyrase/Topo IV-IN-2 can inhibit the biofilms of B. subtilis and MRSA, with an MIC of 1.9 μM against both B. subtilis and MRSA. DNA gyrase/Topo IV-IN-2 can be used in research related to anti-drug-resistant bacterial drugs.
    DNA gyrase/Topo IV-IN-2
  • HY-161097
    Antibacterial agent 171
    		Inhibitor
    Antibacterial agent 171 (Compound 28) is an antibacterial agent. Antibacterial agent 171 inhibits gram-negative bacteria.
    Antibacterial agent 171
  • HY-179383
    DprE1-IN-14
    		Inhibitor
    DprE1-IN-14 (Compound 77) is a DprE1 inhibitor, with an IC50 value of 2.5 nM for M. tb. DprE1-IN-14 exhibits anti-tuberculosis activity, with an MIC₉₀ of 0.3 μM for the M. tb mc26230 strain. DprE1-IN-14 mainly shows bacteriostatic activity, demonstrating a time-dependent bactericidal effect at 10-fold MIC concentrations. DprE1-IN-14 can be used in anti-tuberculosis research.
    DprE1-IN-14
  • HY-121341R
    Brodimoprim (Standard)
    		Inhibitor
    Brodimoprim (Standard) is the analytical standard of Brodimoprim. This product is intended for research and analytical applications. Brodimoprim (Ro 10-5970), a trimethoprim analogue, is an orally active dihydrofolate reductase inhibitor. Brodimoprim is highly active against a broad spectrum of gram-negative and gram-positive bacteria.
    Brodimoprim (Standard)
  • HY-W741028
    Moxifloxacin N-sulfate disodium
    		Inhibitor
    Moxifloxacin N-sulfate disodium is an anionic sulfonate derivative of Moxifloxacin (HY-66011A). Moxifloxacin is an 8-methoxyquinolone antibacterial antibiotic used in the research of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and infectious pneumonia.
    Moxifloxacin N-sulfate disodium
  • HY-B0147AR
    Pefloxacin mesylate (Standard)
    		Inhibitor
    Pefloxacin mesylate (Standard) (Pefloxacinium mesylate (Standard)) is the analytical standard of Pefloxacin mesylate (HY-B0147A). This product is intended for research and analytical applications. Pefloxacin (Pefloxacinium) mesylate is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin mesylate inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin mesylate exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin mesylate has anti-Plasmodium yoelii infection activity. Pefloxacin mesylate increase UVA-induced edema and immunesuppression. Pefloxacin mesylate can be used for infection studies.
    Pefloxacin mesylate (Standard)
  • HY-161239
    (S)-IB-96212
    		Inhibitor
    (S)-IB-96212 (compound 4), an oligomycin derivative, inhibits the MurD2 reaction, but not the MurL reaction. (S)-IB-96212 is a specific inhibitor of the alternative pathway of peptidoglycan biosynthesis. (S)-IB-96212 weakly inhibits the MurD reaction.
    (S)-IB-96212
  • HY-N15101
    Rifamycin L
    		Inhibitor
    Rifamycin L has the antibacterial action.
    Rifamycin L
  • HY-N14899
    Oxasetin
    		Inhibitor
    Oxasetin has medium activity against Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecalis (MIC is 16 μg/mL). Oxasetin has no activity against Gram-negative bacteria and fungi.
    Oxasetin
  • HY-16742BR
    Gepotidacin mesylate hydrate (Standard)
    		Inhibitor
    Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases.
    Gepotidacin mesylate hydrate (Standard)
  • HY-N12954
    (R)-Mucronulatol
    		Inhibitor
    (R)-Mucronulatol is a flavonoid that can be isolated from Astragalus adsurgens. (R)-Mucronulatol shows antibacterial activity against Escherichia coli, Bacillus cereus, Staphylococcus aureus, Erwinia carotovora and Bacillus subtili, with MICs of 15.5, 15.5, 7.8, 7.8, 15.5 μg/mL respectively.
    (R)-Mucronulatol
  • HY-N14254
    Hypelcin A-Ⅰ
    		Inhibitor
    Hypelcin A-I has anti-Gram-negative bacterial and fungal activity.
    Hypelcin A-Ⅰ
  • HY-N3031R
    Grosvenorine (Standard)
    		Inhibitor
    Grosvenorine (Standard) is the analytical standard of Grosvenorine. This product is intended for research and analytical applications. Grosvenorine is an orally active flavonoid glycoside found in S. grosvenorii. Grosvenorine exhibits antibacterial, antioxidant and antiinflammation activities. Grosvenorine can induce apoptosis and increases anti-apoptotic Bcl-2 protein expression and reduces pro-apoptotic P53 protein expression in gastric tissues. Grosvenorine enhances mucin/glycoprotein secretion, regulates gastric pH, and reduces gastric lesion incidence.Grosvenorine increases glutathione peroxidase, catalase, and SOD levels, reduces lipid peroxidation (MDA), and lowers TNF-α and IL-6 levels. Grosvenorine can be used for the researches of bacterial infection and Gastric ulcer.
    Grosvenorine (Standard)
  • HY-173417
    Antibacterial agent 275
    		Inhibitor
    Antibacterial agent 275 (Ⅲ1) is a antibacterial agent, with a λmax of 730 nm. Antibacterial agent 275 (Ⅲ1) can be used in the research for antimicrobial photodynamic therapy (aPDT).
    Antibacterial agent 275
  • HY-W040220
    N-(3-Hydroxyoctanoyl)-DL-homoserine lactone
    		Inhibitor
    N-(3-Hydroxyoctanoyl)-DL-homoserine lactone (Compound 40) is a competitive inhibitor of the quorum sensing receptor LuxR with an IC50 value of 4 μM. N-(3-Hydroxyoctanoyl)-DL-homoserine lactone shows selective inhibition toward quorum sensing systems in Gram-negative bacteria like Pseudomonas aeruginosa. N-(3-Hydroxyoctanoyl)-DL-homoserine lactone is promising for research of bacterial infections.
    N-(3-Hydroxyoctanoyl)-DL-homoserine lactone
Cat. No. Product Name / Synonyms Application Reactivity