2. Vías de señalización
  3. Epigenetics
  4. Epigenetic Reader Domain
  5. BET Isoform
  6. BET Inhibitor

BET Inhibitor

BET Inhibitors (5):

Cat. No. Nombre del producto Efecto Pureza
  • HY-112588
    dBET6
    		Inhibitor 99.92%
    dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET, with an IC50 of 14 nM, and has antitumor activity.
  • HY-78695
    JQ-1 carboxylic acid
    		Inhibitor 99.69%
    JQ-1 carboxylic acid, a (+)-JQ-1 (HY-13030) derivative, is a potent BET bromodomain inhibitor. JQ-1 carboxylic acid can be used to synthesize PROTAC, which can target the degradation of BRD4.
  • HY-181003
    GSK785
    		Inhibitor
    GSK785 is a BRD2/4-selective, BRD3-sparing bivalent BET inhibitor. GSK785 inhibits production of the MCP1 cytokine in human whole blood. GSK785 can be used for the research of cancer.
  • HY-182036
    KWZL-7f15
    		Inhibitor
    KWZL-7f15 is a dual CDK6/BRD4 inhibitor with an IC50 of 31.81 nM against human CDK6. KWZL-7f15 inhibits the CDK6-RB axis and BRD4-Myc axis, and also acts as a pan-BET inhibitor. KWZL-7f15 exhibits antiproliferative activity against triple-negative breast cancer cells. KWZL-7f15 shows antitumor activity in xenograft mouse models. KWZL-7f15 can be used in studies related to triple-negative breast cancer.
  • HY-161387
    EBET-590
    		Inhibitor
    EBET-590 is a BET inhibitor, and can be used for cancer research