HBV
Hepatitis B virus
HBV (Hepatitis B virus), abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. HBV causes the disease hepatitis B. The hepatitis B virus is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and theWoolly monkey hepatitis B virus. The genus is classified as part of the Hepadnaviridae family. HBV is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins, and into eight genotypes (A–H) according to overall nucleotide sequence variation of the genome. The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus. Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment and possibly vaccination.
All Product Categories
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HBV Related Products (383)
Related Products (383)
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Antibodies (2)
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Valtorcitabine dihydrochloride
0 ImagesCat. No.: HY-127122CAS No.: 359689-54-6Valtorcitabine dihydrochloride is a prodrug of L-deoxycytidine and also is an HBV inhibitor.
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LPRP-Et-97543
0 ImagesCat. No.: HY-N8168CAS No.: 84638-48-2LPRP-Et-97543 is a potent anti-HBV agent. LPRP-Et-97543 reduces Core, S, and preS but not X promoter activities. LPRP-Et-97543 can be used for acute and chronic HBV infections research.
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LB80317
0 ImagesCat. No.: HY-106235CAS No.: 441785-24-6
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Junceellolide C
0 ImagesCat. No.: HY-N10404CAS No.: 121769-82-2
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HBV-IN-31
0 ImagesCat. No.: HY-148782CAS No.: 2413192-95-5HBV-IN-31 is a potent cccDNA (covalently closed circular DNA) inhibitor. HBV-IN-31 shows anti-HBV activity with an IC50 value of 0.13 µM for HBsAg. HBV-IN-31 inhibits cell growth.
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HEC72702
0 ImagesCat. No.: HY-123767CAS No.: 1793063-59-8HEC72702 is a potent and orally active hepatitis B virus capsid inhibitor with an EC50 values of 0.039 µM. HEC72702 dose-dependently reduced HBV DNA in both the plasma and livers.
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AT-61
0 ImagesCat. No.: HY-114956CAS No.: 300669-68-5
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Tomligisiran sodium scrambled negative control
0 ImagesCat. No.: HY-177667BTomligisiran sodium scrambled negative control is the sequence scrambled negative control of Tomligisiran sodium.
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Nirtetralin
0 ImagesCat. No.: HY-187042CAS No.: 50656-78-5Nirtetralin is a lignan. Nirtetralin can be isolated from Phyllanthus urinaria, Phyllanthus virgatus Forst. f., and Phyllanthus niruri L. Nirtetralin undergoes metabolic activation to generate active intermediates, such as nitroalkene ions and nitroso compounds, which can form DNA adducts and induce DNA damage. Nirtetralin induces ROS production in cells. Nirtetralin blocks the epithelial-mesenchymal transition process of cancer cells by altering the expression of related markers. Nirtetralin inhibits the production of HBsAg and HBeAg. Nirtetralin exhibits anticancer activity against oral squamous cell carcinoma. Nirtetralin can be used in studies of oral squamous cell carcinoma and hepatitis B virus infection.
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Xalnesiran
0 ImagesCat. No.: HY-145638CAS No.: 2538784-48-2Synonyms: RO7445482Xalnesiran (RO7445482) is a small interfering RNA molecule that targets a conserved region of the
hepatitis B virus (HBV) genome. Xalnesiran can be used for the research of chronic hepatitis B infection.
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Glaziovine
0 ImagesCat. No.: HY-W754691CAS No.: 6808-72-6
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HBV-IN-16
0 ImagesCat. No.: HY-144047CAS No.: 2355225-38-4HBV-IN-16 is a potent inhibitor of covalently closed circular DNA (cccDNA). cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-16 is a quinoline derivative. HBV-IN-16 has the potential for the research of HBV infection (extracted from patent WO2019121357A1, compound 1).
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HBV-IN-21
0 ImagesCat. No.: HY-146011CAS No.: 2460957-52-0
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HBV-IN-18
0 ImagesCat. No.: HY-144322CAS No.: 2766688-73-5HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) with an EC50 of 2790 nM.
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Telbivudine-d4
0 ImagesCat. No.: HY-B0017SCAS No.: 1134182-00-5Synonyms: Epavudine-d4; L-Thymidine-d4; NV 02B-d4
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Tomligisiran sodium
0 ImagesCat. No.: HY-177667A
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Oxynitidine
0 ImagesCat. No.: HY-W676876CAS No.: 548-31-2
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Ozisiran sodium scrambled negative control
0 ImagesCat. No.: HY-177654BOzisiran sodium scrambled negative control is the sequence scrambled negative control of Ozisiran sodium.
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HBV/HDV-IN-3
0 ImagesCat. No.: HY-163580CAS No.: 2883679-03-4
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Taribavirin
0 ImagesCat. No.: HY-10545CAS No.: 119567-79-2Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin, is a ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia.
