1. Anti-infection
  2. HBV
    HCV
  3. Taribavirin

Taribavirin 

Cat. No.: HY-10545
Handling Instructions

Taribavirin is an inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin, is a ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia.

For research use only. We do not sell to patients.

Taribavirin Chemical Structure

Taribavirin Chemical Structure

CAS No. : 119567-79-2

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Description

Taribavirin is an inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus[1]. Taribavirin, is a ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia[2].

In Vitro

Taribavirin (0-2 μM; 24 hours) significantly induces MCF-7 cell death, recording half inhibitory effect (IC50) of 0.756 μM in MCF-7 cells[1].

Cell Viability Assay[1]

Cell Line: MCF-7 cells
Concentration: 0 μM, 0.1 μM, 1 μM, 2 μM
Incubation Time: 24 hours
Result: Decreased MCF-7 cell growth.
Molecular Weight

243.22

Formula

C₈H₁₃N₅O₄

CAS No.

119567-79-2

SMILES
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Taribavirin
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