1. Anti-infection
  2. HBV
    HCV
  3. Taribavirin hydrochloride

Taribavirin hydrochloride 

Cat. No.: HY-10545A Purity: 98.21%
Handling Instructions

Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia.

For research use only. We do not sell to patients.

Taribavirin hydrochloride Chemical Structure

Taribavirin hydrochloride Chemical Structure

CAS No. : 40372-00-7

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1 mg USD 150 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia[2].

IC50 & Target

Inosine monophosphate dehydrogenase[1]

In Vitro

Taribavirin hydrochloride (0-2 μM; 24 hours) significantly induces MCF-7 cell death, recording half inhibitory effect (IC50) of 0.756 μM in MCF-7 cells[1].

Cell Viability Assay[1]

Cell Line: MCF-7 cells
Concentration: 0 μM, 0.1 μM, 1 μM, 2 μM
Incubation Time: 24 hours
Result: Decreased MCF-7 cell growth.
Molecular Weight

279.68

Formula

C₈H₁₄ClN₅O₄

CAS No.

40372-00-7

SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

TaribavirinHBVHCVHepatitis B virusHepatitis C virusInhibitorinhibitorinhibit

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Taribavirin hydrochloride
Cat. No.:
HY-10545A
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