2. Signaling Pathways
  3. Immunology/Inflammation
  4. IRAK
  5. IRAK1 Isoform
  6. IRAK1 Inhibitor

IRAK1 Inhibitor

IRAK1 Inhibitors (8):

Cat. No. Product Name Effect Purity
  • HY-103017
    JH-X-119-01 hydrochloride
    		Inhibitor ≥98.0%
    JH-X-119-01 hydrochloride is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor.
  • HY-N0039
    Ginsenoside Rb1
    		Inhibitor 98.75%
    Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with an IC50 of 6.3±1.0 μM.
  • HY-147141
    HS-276
    		Inhibitor 98.59%
    HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM.
  • HY-111101
    AZ1495
    		Inhibitor 98.18%
    AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor.
  • HY-103017A
    JH-X-119-01
    		Inhibitor ≥98.0%
    JH-X-119-01 is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor.
  • HY-153110A
    Larotinib mesylate hydrate
    		Inhibitor
    Larotinib mesylate hydrate is a potent broad-spectrum and orally active tyrosine kinase inhibitor (TKI) with EGFR as the main target with an IC50 of 0.6 nM.
  • HY-153110
    Larotinib
    		Inhibitor
    Larotinib is a potent broad-spectrum and orally active tyrosine kinase inhibitor (TKI) with EGFR as the main target with an IC50 of 0.6 nM.
  • HY-134911
    HS-243
    		Inhibitor 99.88%
    HS-243 is a potent and selective IRAK-4 and IRAK-1 inhibitor, with IC50 values of 20 and 24 nM.