PROTACs Modulator

PROTACs Modulators (6):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-141877

MS4322 2375432-47-4 98.28%

MS4322 (YS43-22) is a first-in-class PRMT5 degrader and a valuable chemical tool (PROTAC) for exploring the PRMT5 functions in health and disease.

MS4322	2375432-47-4	98.28%
MS4322 (YS43-22) is a first-in-class PRMT5 degrader and a valuable chemical tool (PROTAC) for exploring the PRMT5 functions in health and disease.

MS4322 (isomer)	2601727-80-2	99.22%
MS4322 (YS43-22) isomer is an isomer of MS4322. MS4322 is a potent and selective PRMT5 (protein arginine methyltransferase 5) degrader, and inhibits growth of multiple cancer cell lines.

HY-139682

Dovitinib-RIBOTAC 2759351-68-1 98.93%

Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.
HY-139682A

Dovitinib-RIBOTAC TFA 2759351-69-2

Dovitinib RIBOTAC TFA is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.
HY-142662

PROTAC IRAK3 degrade-1 2712600-00-3

PROTAC IRAK3 degrade-1 (compound 23) is a potent and selective degrader of IRAK3 (IC₅₀ = 5 nM).

Dovitinib-RIBOTAC	2759351-68-1	98.93%
Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.

Dovitinib-RIBOTAC TFA	2759351-69-2
Dovitinib RIBOTAC TFA is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.

PROTAC IRAK3 degrade-1	2712600-00-3
PROTAC IRAK3 degrade-1 (compound 23) is a potent and selective degrader of IRAK3 (IC₅₀ = 5 nM).

di-Ellipticine-RIBOTAC	2767983-76-4
di-Ellipticine-RIBOTAC is a dual-function small molecule that reduces c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo amyotrophic lateral sclerosis (ALS ) models.

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