Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Verwandte Produkte (1734):

By Effects:	Inhibitor (1) Chemical (1)

Art. -Nr.	Produktname	Wirkung	Reinheit	Chemical Structure

HY-W007722

H-Ala-OtBu.HCl		98.0%
H-Ala-OtBu.HCl is an alanine derivative.

HY-W343900

Hydroxyproline		98.0%
Hydroxyproline (DL-Hydroxyproline) is a non-essential amino acid and one of the main components of collagen tissue. Hydroxyproline can be used in research on endocrine and metabolic diseases, as well as genetic diseases and malformations. Hydroxyproline can also serve as a biomarker.

HY-W008235

Fmoc-N-Me-Ala-OH		99.92%
Fmoc-N-Me-Ala-OH is an Fmoc-protected N-methyl-L-alanine and also a building block for solid-phase peptide synthesis. As a building block, Fmoc-N-Me-Ala-OH is used to synthesize peptidomimetic antagonists of XIAP BIR3 derived from Smac/DIABLO.

HY-78733

N-Fmoc-L-valine N-succinimidyl ester		99.88%
N-Fmoc-L-valine N-succinimidyl ester is a valine derivative.

HY-W009412

Boc-D-Phe-OH		99.93%
Boc-D-Phe-OH is a phenylalanine derivative.

HY-Y1030

tert-Butyl L-valinate hydrochloride		98.0%
tert-Butyl L-valinate hydrochloride is a valine derivative.

HY-W048700

FMOC-D-Allo-THR(TBU)-OH		99.86%
FMOC-D-Allo-THR(TBU)-OH is a D-allothreonine derivative.

HY-34540

(αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-pyridinepropanoic acid		99.94%
(αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-pyridinepropanoic acid is an alanine derivative.

HY-137529

Nα-Benzoyl-L-arginine 4-nitroanilide hydrochloride		99.92%
Nα-Benzoyl-L-arginine 4-nitroanilide (hydrochloride) is aarginine derivatives.

HY-W141936

Phe-Gly
Phe-Gly hydrate is a Glycine (HY-Y0966) derivative.

HY-W097491

L-Methionine sulfone		99.95%
L-Methionine sulfone is a sulfonic acid derivative of L-Methionine (HY-N0326). L-Methionine in the presence of a number of oxidizing systems is readily converted to L-Methionine sulfone.

HY-W007615

H-Phe(4-I)-OH		99.77%
H-Phe(4-I)-OH is a phenylalanine derivative.

HY-W023145

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butylthio)-L-cysteine		99.91%
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butylthio)-L-cysteine is a cysteine derivative.

HY-79680

(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid		99.96%
(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a phenylalanine derivative.

HY-W009006

Fmoc-B-HoPhe-OH		99.14%
Fmoc-B-HoPhe-OH is a phenylalanine derivative.

HY-78927

N-Boc-L-Prolinal		98.81%
N-Boc-L-Prolinal is a proline with a Boc protecting group, which can be used to synthesize biologically active peptide mimetics, such as the synthesis of Dolastatin 10 (HY-15580) analogs with anti-colon cancer activity.

HY-W008529

Fmoc-N-Me-Glu(OtBu)-OH		99.67%
Fmoc-N-Me-Glu(OtBu)-OH is a glutamic acid derivative.

HY-W008560

Fmoc-Gly(allyl)-OH		99.94%
Fmoc-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative.

HY-W014553

N-Acetyl-D-phenylalanine		99.81%
N-Acetyl-D-phenylalanine is a phenylalanine derivative.

HY-W008446

(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid		99.80%
(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid is a proline derivative.

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