2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Carbamoyl Phosphate Synthetase (CPS)
  5. CPS I Isoform
  6. CPS I Inhibitor

CPS I Inhibitor

CPS I Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-136128
    H3B-120
    		Inhibitor 98.36%
    H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity.
  • HY-183888
    H3B-616
    		Inhibitor
    H3B-616 is a selective carbamoyl phosphate synthetase 1 (CPS1) inhibitor with a human IC50 of 66 nM. H3B-616 binds to an allosteric pocket in the CPS1 integrating domain to exert target engagement and inhibit enzyme activity. H3B-616 can be used for the research of nonsmall cell lung cancer and gastric cancer.