2. シグナル伝達
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative 関連製品 (3819):

製品番号 製品名 製品効果 純度 構造式
  • HY-134280
    8-Br-NHD+
    8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog.
    8-Br-NHD+
  • HY-N14553
    Antcin C
    Antcin C is an ergostane-type triterpenoid. Antcin C can be found in Antrodia cinnamomea.
    Antcin C
  • HY-P10885
    Lead-lapemelanotide zapixetan
    Lead-lapemelanotide zapixetan is a precursor of lapemelanotide, which can be used in life science research.
    Lead-lapemelanotide zapixetan
  • HY-N7896
    (+)-Corypalmine
    (+)-Corypalmine ((+)-Discretinine) is a natural alkaloid.
    (+)-Corypalmine
  • HY-105060
    TA 077
    TA 077 is a nitrosourea derivative with antitumor activity. TA 077 can be used for the research of cancer, such as lung cancer and leukemia.
    TA 077
  • HY-N17470
    3-Deoxyartselaenin C
    3-Deoxyartselaenin C is a natural product that can be found in corn.
    3-Deoxyartselaenin C
  • HY-N16765
    Fibraurin
    Fibraurin is a natural diterpene.
    Fibraurin
  • HY-W702070
    Nor mianserin
    Nor mianserin (Desmethylmianserin) is a compound with similar biological activity to Mianserin (HY-B0188), but with lower potency. Mianserin is a serotonin inhibitor and antihistamine compound.
    Nor mianserin
  • HY-13631T
    (1R,9S)-Exatecan
    (1R,9S)-Exatecan (DX8951f) is the (1R,9S) stereoisomer of Exatecan (HY-13631). Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
    (1R,9S)-Exatecan
  • HY-N7283
    Glabralide B
    Glabralide B is a natural phenolic compound.
    Glabralide B
  • HY-W780517
    (3β)-3-Hydroxyergost-5-en-7-one
    (3β)-3-Hydroxyergost-5-en-7-one is a natural steroid.
    (3β)-3-Hydroxyergost-5-en-7-one
  • HY-N17120
    1,5-Epoxy-3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane
    1,5-Epoxy-3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane is a natural phenolic compound.
    1,5-Epoxy-3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)heptane
  • HY-N17513
    4'-Methoxy-pinoresinol
    4'-Methoxy-pinoresinol is a natural product that can be found in Forsythia suspensa?(Thunb.) Vahl.
    4'-Methoxy-pinoresinol
  • HY-N17214
    Comososide
    Comososide is a natural terpenoid.
    Comososide
  • HY-173584
    GSK484-Ph
    GSK484-Ph (compound 15d) is an analog of GSK484 (HY-100514) with potent anticancer effects. GSK484-Ph potently inhibits 4T1 cells and can be used for the study of breast cancer.
    GSK484-Ph
  • HY-W740221
    7-Ethylcamptothecin-d3-1
    7-Ethylcamptothecin-d3-1 is the deuterium labeled 7-Ethylcamptothecin (HY-N2108). 7-Ethylcamptothecin is a derivative of Camptothecin (HY-16560) and a key intermediate in the synthesis of SN-38 (HY-13704). 7-Ethylcamptothecin can be used in tumor-related research.
    7-Ethylcamptothecin-d<sub>3</sub>-1
  • HY-N16131
    Sydonic acid
    Sydonic acid is a bisabolane-type sesquiterpenoid that can be isolated from the fungus Aspergillus sydowii BTBU20213012, which was obtained from a marine sediment sample in the Western Pacific.
    Sydonic acid
  • HY-19159
    CGP-43371
    CGP-43371, a Rifampicin (HY-B0272) derivative, is an orally active hypolipidemic agent. CGP-43371 has hypolipidemic and anti-atherosclerotic activities.
    CGP-43371
  • HY-122036
    Flumedroxone acetate
    Flumedroxone acetate is an active compound.
    Flumedroxone acetate
  • HY-N11730
    6',7'-Epoxyrotenone
    6',7'-Epoxyrotenone is a derivative and photodegradation product of Rotenone (HY-B1756), with an acute intraperitoneal LD50 of 7.2 mg/kg in mice.
    6',7'-Epoxyrotenone