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United States

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Cat. No.: HY-173584

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GSK484-Ph

GSK484-Ph (compound 15d) is an analog of GSK484 (HY-100514) with potent anticancer effects. GSK484-Ph potently inhibits 4T1 cells and can be used for the study of breast cancer.

For research use only. We do not sell to patients.

Formula: C₃₀H₃₂ClN₅O₃
Molecular Weight:546.06

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

GSK484-Ph Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

GSK484-Ph (compound 15d) is an analog of GSK484 (HY-100514) with potent anticancer effects. GSK484-Ph potently inhibits 4T1 cells and can be used for the study of breast cancer^[1].

Chemical Information

Molecular Weight 546.06
Formula C₃₀H₃₂ClN₅O₃
SMILES

COC1=C2C(N=C(N2C)C3=CC4=C(N3CC5=CC=CC=C5)C=CC=C4)=CC(C(N6CC[C@H]([C@H](C6)N)O)=O)=C1.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Guo, Z., et al. Synthesis of reversible PAD4 inhibitors via copper-catalyzed C−H arylation of benzimidazole. Sci. China Chem. 62(6), 592-596 (2019).

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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