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Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative 関連製品 (3819):

製品番号 製品名 製品効果 純度 構造式
  • HY-16208
    Fluorapacin
    Fluorapacin is an anti-tumor agent.
    Fluorapacin
  • HY-N3744
    Dihydrocitflavanone
    Dihydrocitflavanone is a natural flavonoid.
    Dihydrocitflavanone
  • HY-N9800
    3β-Hydroxycinnamolide
    3β-Hydroxycinnamolide is a natural sesquiterpene.
    3β-Hydroxycinnamolide
  • HY-148603
    Dupracetam
    Dupracetam is a Piracetam (HY-B0585) analog. Dupracetam antagonizes the lethality of HC-3.
    Dupracetam
  • HY-N3405A
    (±)-Lariciresinol
    (±)-Lariciresinol is a natural lignan.
    (±)-Lariciresinol
  • HY-N17082
    Anisolactone
    Anisolactone is a natural coumarin.
    Anisolactone
  • HY-105400
    NIP 502
    NIP 502 is a pyridazinone derivative with orally active anti-inflammation and anti-immunology effects. NIP 502 can be used for the research of asthma.
    NIP 502
  • HY-114946
    N-methyl-4,4-difluoro Modafinil
    N-methyl-4,4-difluoro Modafinil is categorized as a nootropic.
    N-methyl-4,4-difluoro Modafinil
  • HY-N18375
    7-Gingerdiol
    7-Gingerdiol is a ginger phenol found in Zingiber officinale rhizomes.
    7-Gingerdiol
  • HY-W353602
    Aleoe-emodin triacetate 98.06%
    Aleoe-emodin triacetate is an Anthraquinone (HY-N0354) derivative, and can be isolated from leaves of Kniphofia foliosa.
    Aleoe-emodin triacetate
  • HY-N2099A
    (Z)-Onjisaponin B
    (Z)-Onjisaponin B ((Z)-Senegin III) is a derivative of Onjisaponin B (HY-N2099). Onjisaponin B is an orally active natural product derived from Polygala tenuifolia. Onjisaponin B inhibits NF-κB p65. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin. Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis. Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB.
    (Z)-Onjisaponin B
  • HY-N16900
    3-O-Methyltagitinin F
    3-O-Methyltagitinin F is a natural sesquiterpene.
    3-O-Methyltagitinin F
  • HY-N17423
    Euphpekinensin
    Euphpekinensin is a natural product that can be found in Euphorbia.
    Euphpekinensin
  • HY-120415
    RK 397
    RK 397 is an active compound.
    RK 397
  • HY-N0722A
    (Z)-Neochlorogenic acid
    (Z)-Neochlorogenic acid is the z-isomer of Neochlorogenic acid (HY-N0722). Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants. Neochlorogenic acid inhibits the production of TNF-α and IL-1β. Neochlorogenic acid suppresses iNOS and COX-2 protein expression. Neochlorogenic acid also inhibits phosphorylated NF-κB p65 and p38 MAPK activation.
    (Z)-Neochlorogenic acid
  • HY-158839
    4-Ethyl pentedrone hydrochloride
    4-Ethyl pentedrone (p-Ethyl-α-methylamino-valerophenone) hydrochloride is a drug derivative.
    4-Ethyl pentedrone hydrochloride
  • HY-114660
    9,11-Methane-epoxy prostaglandin F1α
    9,11-methane-epoxy Prostaglandin F1α (9,11-Epoxymethano PGH1; 9,11-methane-epoxy PGF1α) is a derivative of prostaglandin H1. 9,11-methane-epoxy Prostaglandin F1α induces aggregation of isolated rabbit platelets (EC50=0.88 µM) and contraction of rabbit aortic strips (EC50=0.11 µM). 9,11-methane-epoxy Prostaglandin F1α induces contraction of isolated guinea pig tracheas (EC50 = 3.4 µM).
    9,11-Methane-epoxy prostaglandin F1α
  • HY-180332
    NSC-624871
    NSC-624871 (JD-87), an analog of Miltefosine (HY-13685), is natural killer T-2 (NKT-2) activator. NSC-624871 activates type II NKT cells. NSC-624871 can be used for the study of SARS-CoV-2-mediated inflammatory conditions.
    NSC-624871
  • HY-176869
    EMC-AANL-DOX
    EMC-AANL-DOX is a legumain-activated prodrug conjugate of Doxorubicin (DOX) (HY-15142A). EMC-AANL-DOX shows antitumor activity in mouse models of neuroblastoma (NB), breast cancer (4T1), fibrosarcoma (HT1080), and colorectal cancer liver metastases (CT26). EMC-AANL-DOX can be used for cancer research.
    EMC-AANL-DOX
  • HY-N16992
    N-Tetracosanoyltyramine
    N-Tetracosanoyltyramine is a natural alkaloid.
    N-Tetracosanoyltyramine