2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N17295
    Clerosterol
    Clerosterol is a natural product that can be found in Chitong.
    Clerosterol
  • HY-175107
    3-Fluoro-α-ethylaminobutiophenone hydrochloride
    3-Fluoro-α-ethylaminobutiophenone (3-Fluoro-N-ethylbuphedrone; 3F-NEB) hydrochloride is a drug analogue and can be used for the research of neurological disease.
    3-Fluoro-α-ethylaminobutiophenone hydrochloride
  • HY-N17087
    (rel)-3-Hydroxy-p-menth-1-en-6-one
    (rel)-3-Hydroxy-p-menth-1-en-6-one is a natural terpenoid.
    (rel)-3-Hydroxy-p-menth-1-en-6-one
  • HY-119761
    L-670,548
    L-670,548 is an active compound.
    L-670,548
  • HY-105281
    rel-(E)-BMY 21950 sodium
    rel-(E)-BMY 21950 sodium is the relative configuration of BMY 21950 (HY-105281A). BMY 21950 is an HMG-CoA reductase inhibitor. BMY 21950 inhibits hepatic cholesterol synthesis.
    rel-(E)-BMY 21950 sodium
  • HY-133854
    L 8412
    L 8412 is a potent anti-adrenergic agent and anti-anginal agent.
    L 8412
  • HY-N18215
    Ginsenoside mRb2
    Ginsenoside mRb2 is a protopanaxadiol-type ginsenoside.
    Ginsenoside mRb2
  • HY-N19715
    Asperosaponin H1
    Asperosaponin H1 is a triterpenoid saponin (octasaccharide saponin) found in the roots of Dipsacus asperoides C.Y. Cheng et T.M. Ai. Asperosaponin H1 can be used for research on liver and kidney diseases.
    Asperosaponin H1
  • HY-N15560
    Thaigranatumin G
    Thaigranatumin G is a protolimonoid compound found in the seeds of the Thai mangrove (Xylocarpus granatum). Thaigranatumin G is promising for research of neurodegenerative diseases such as Parkinson's diseases.
    Thaigranatumin G
  • HY-N17121
    Ent-11β,18-dihydroxy-16α,17-isopropylidenedioxyatisan-3-one
    Ent-11β,18-dihydroxy-16α,17-isopropylidenedioxyatisan-3-one is a natural diterpene.
    Ent-11β,18-dihydroxy-16α,17-isopropylidenedioxyatisan-3-one
  • HY-N17428
    (2E,4E)-N-(2-Methylpropyl)hexadeca-2,4-dienamide
    (2E,4E)-N-(2-Methylpropyl)hexadeca-2,4-dienamide is a natural product that can be found in chili.
    (2E,4E)-N-(2-Methylpropyl)hexadeca-2,4-dienamide
  • HY-N17057
    Marsdenoside I
    Marsdenoside I is a natural steroid.
    Marsdenoside I
  • HY-182302
    SMTIN-P01
    SMTIN-P01 is a TRAP1 inhibitor that is selective for cytosolic Hsp90 and accumulates in mitochondria. SMTIN-P01 binds to the ATP-binding site of TRAP1 as an ATP mimic, thereby inhibiting ATPase and foldase activities. SMTIN-P01 induces mitochondrial membrane depolarization and proteolytic degradation in cancer cells. SMTIN-P01 exhibits significant cytotoxicity, but shows extremely low toxicity to primary mouse hepatocytes, and does not interfere with SIRT3-related functions or the levels of cytosolic Hsp90 substrates. SMTIN-P01 has important application value in cancer-related research.
    SMTIN-P01
  • HY-168068
    Res-Glu3
    Res-Glu3 is the derivative of Resveratrol (HY-16561). Res-Glu3 mitigates the ROS accumulation, and exhibits neuroprotective efficacy against H2O2-caused cellular damage in PC12. Res-Glu3 exhibits antioxidant activity in rats ischemia reperfusion models.
    Res-Glu3
  • HY-113690
    AHN 086
    AHN 086 is an active compound.
    AHN 086
  • HY-19521
    SRX251
    SRX251 is an active compound.
    SRX251
  • HY-123161
    JBIR-15
    JBIR-15 is a new aspochracin derivative. JBIR-15 is isolated from a sponge-derived fungus, Aspergillus sclerotiorum Huber Sp080903f04.
    JBIR-15
  • HY-W748405
    10-Aminocamptothecin
    10-Aminocamptothecin is a derivative of Camptothecin (HY-16560).
    10-Aminocamptothecin
  • HY-N9776
    6''-O-Acetylsaikosaponin b3
    6''-O-Acetylsaikosaponin b3 is a natural triterpene.
    6''-O-Acetylsaikosaponin b3
  • HY-18003
    Oleanolic acid derivative 2
    Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.
    Oleanolic acid derivative 2