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  3. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3823):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N16884
    Dodovisone C
    Dodovisone C is a natural flavonoid.
    Dodovisone C
  • HY-124880
    JNJ-28330835
    JNJ-28330835 is an active compound.
    JNJ-28330835
  • HY-120474
    Ro 23-0364
    Ro 23-0364 is an oral active imidazobenzodiazepine agent with mixed benzodiazepine. Ro 23-0364 shows sedative and can be used for study of neurological disease.
    Ro 23-0364
  • HY-168113
    Antiproliferative agent-60
    Antiproliferative agent-60 (compound 8c) is a 11-Azaartemisinin derivative with superior anticancer activities. Antiproliferative agent-60 shows IC50 values of 7.7 μM, 42.5 μM, and 15.5 μM for epidermoid carcinoma (KB), HepG2, and A549 cells, respectively. Antiproliferative agent-60 exhibits significant tumor selectivity, up to 32-fold higher compared to Hek293 normal cells.
    Antiproliferative agent-60
  • HY-146467
    Anticancer agent 62
    Anticancer agent 62 (compound 4c) is a potent anticancer agent. Anticancer agent 62 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 0.019, 0.060 and 0.016 μM, respectively. Anticancer agent 62 shows effective tumor growth inhibition.
    Anticancer agent 62
  • HY-N19793
    Derrisaponin B
    Derrisaponin B is an oleanane-type triterpenoid saponin and sweetener found in the stems of Derris eriocarpa How, with sweetness intensity approximately 2 times that of Sucrose (HY-B1779) at 1% concentration. Derrisaponin B exhibits sweet taste activity. Derrisaponin B can be used for research on hypertension, hyperglycemia, and obesity.
    Derrisaponin B
  • HY-N16705
    Butyl rosmarinate
    Butyl rosmarinate is a natural lignan.
    Butyl rosmarinate
  • HY-N7874
    Celangulatin F
    Celangulatin F is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..
    Celangulatin F
  • HY-N17129
    Disporopsin
    Disporopsin is a natural flavonoid.
    Disporopsin
  • HY-156860
    WP 1122
    WP 1122 is a 2-deoxy-D-glucose (HY-13966) analog that is a potent cytotoxic agent. WP 1122 is a glycolysis inhibitor. WP 1122 can be used for the research of cancer.
    WP 1122
  • HY-159940
    Ferroptosis/apoptosis inducer-2
    Ferroptosis/apoptosis inducer-2 (compound D2) is an anticancer agent and shows anticancer activity both in vivo and in vitro.
    Ferroptosis/apoptosis inducer-2
  • HY-157072
    WAY-311474
    98.0%
    WAY-311474 is an active molecule for research into amyloid diseases and synucleinopathies.
    WAY-311474
  • HY-N16673
    Fornicin A
    Fornicin A is a natural phenolic compound.
    Fornicin A
  • HY-N17531
    4-(β-D-Glucopyranosyloxy)benzenepropanoic acid
    4-(β-D-Glucopyranosyloxy) benzenepropanoic acid is a phenolic acid glycoside natural product, which has an O-β-D-glucoside structure formed by a phenylpropanoic acid derivative and glucose.
    4-(β-D-Glucopyranosyloxy)benzenepropanoic acid
  • HY-118515
    ATM4 4-Acetoxy analog
    ATM4 4-Acetoxy analog is an impurity in the synthesis of Heroin.
    ATM4 4-Acetoxy analog
  • HY-10276
    GW813893
    GW813893 is an active compound.
    GW813893
  • HY-137962
    Clanobutin
    Clanobutin is an orally active pharmaceutically acceptable N-acylanilinobutyric acid compound. Clanobutin increases gastrointestinal enzyme secretion. Clanobutin tonicizes the cardiovascular system, increases internal organ blood circulation, and boosts heart force. Clanobutin suppresses stomach ulcer formation and exhibits anti-hepatotoxic activity.
    Clanobutin
  • HY-N17446
    Peujaponisin
    Peujaponisin is an angular-type dihydropyranocoumarin that can be found in the roots of Peucedanum japonicum.
    Peujaponisin
  • HY-N17447
    Deshydroxy-asprellol A
    Deshydroxy-asprellol A (compound 4) is a 24-norursane-type nortriterpenoid that can be found in the roots of Ilex asprella.
    Deshydroxy-asprellol A
  • HY-N9023
    Spiratisanin A
    Spiratisanin A is a natural diterpene.
    Spiratisanin A