WAY-311474
Based on 1 Customer Validation
WAY-311474 is an active molecule for research into amyloid diseases and synucleinopathies.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 569313-77-5
- Formula: C15H19Cl2NO2
- Molecular Weight:316.22
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 569313-77-5
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Appearance Solid
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Molecular Weight 316.22
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Formula C15H19Cl2NO2
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Color White to off-white
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SMILES
O=C(COC1=CC=C(C=C1Cl)Cl)NCC2CCCCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (316.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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Amyloid: Congo Red Amyloid Staining
Congo red amyloid staining is a histochemical method used to detect extracellular amyloid deposits in tissue sections based on the affinity of Congo red dye for β-pleated sheet-rich protein aggregates. When bound to amyloid, Congo red produces characteristic apple-green birefringence under polarized light microscopy, which is widely regarded as a diagnostic feature of amyloid deposition in histopathology. The diagnostic principle relies on the combination of dye binding (congophilia) and optical anisotropy under polarized illumination, which distinguishes amyloid from most non-amyloid eosinophilic extracellular deposits in routine histological evaluation. Amyloid identification by Congo red staining remains a cornerstone in diagnostic pathology despite the availability of adjunct methods such as immunohistochemistry and mass spectrometry, particularly because of its ability to localize deposits directly within tissue architecture. The specificity of Congo red-positive deposits is incre
Purity & Documentation
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Data Sheet (240 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1624 mL | 15.8118 mL | 31.6236 mL | 79.0589 mL |
| 5 mM | 0.6325 mL | 3.1624 mL | 6.3247 mL | 15.8118 mL | |
| 10 mM | 0.3162 mL | 1.5812 mL | 3.1624 mL | 7.9059 mL | |
| 15 mM | 0.2108 mL | 1.0541 mL | 2.1082 mL | 5.2706 mL | |
| 20 mM | 0.1581 mL | 0.7906 mL | 1.5812 mL | 3.9529 mL | |
| 25 mM | 0.1265 mL | 0.6325 mL | 1.2649 mL | 3.1624 mL | |
| 30 mM | 0.1054 mL | 0.5271 mL | 1.0541 mL | 2.6353 mL | |
| 40 mM | 0.0791 mL | 0.3953 mL | 0.7906 mL | 1.9765 mL | |
| 50 mM | 0.0632 mL | 0.3162 mL | 0.6325 mL | 1.5812 mL | |
| 60 mM | 0.0527 mL | 0.2635 mL | 0.5271 mL | 1.3176 mL | |
| 80 mM | 0.0395 mL | 0.1976 mL | 0.3953 mL | 0.9882 mL | |
| 100 mM | 0.0316 mL | 0.1581 mL | 0.3162 mL | 0.7906 mL |
WAY-311474 Related Classifications
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