Antiproliferative agent-60
Antiproliferative agent-60 (compound 8c) is a 11-Azaartemisinin derivative with superior anticancer activities. Antiproliferative agent-60 shows IC50 values of 7.7 μM, 42.5 μM, and 15.5 μM for epidermoid carcinoma (KB), HepG2, and A549 cells, respectively. Antiproliferative agent-60 exhibits significant tumor selectivity, up to 32-fold higher compared to Hek293 normal cells.
For research use only. We do not sell to patients.
- Formula: C24H29BrN4O4
- Molecular Weight:517.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 517.42
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Formula C24H29BrN4O4
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SMILES
BrC1=CC=CC(N2C=C(CN3[C@H]4[C@]56C(CC[C@@H](C)C5CC[C@](OO6)(C)O4)[C@@H](C)C3=O)N=N2)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)