2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D2573
    Cy5.5-PEG2000-FA
    Cy5.5-PEG2000-FA is a fluorescently labeled biomolecule consisting of Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5.5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5.5 is approximately 710 nm.
    Cy5.5-PEG2000-FA
  • HY-D2836C
    FITC-HA (MW 100000)
    FITC-HA (MW 100000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM).
    FITC-HA (MW 100000)
  • HY-D1123
    Indigosol brown IBR
    Indigosol brown IBR is a dye commonly used for dyeing textiles.
    Indigosol brown IBR
  • HY-D1039
    Disperse blue ANT
    Disperse blue ANT is a blue dye commonly used for fiber dyeing.
    Disperse blue ANT
  • HY-D1522
    N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine
    N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine is a fluorescent reagent.
    N,N'-Bis[2-(acetamido)ethyl]-N,N'-dimethyl rhodamine
  • HY-D1824
    Vari Fluor 488 Carboxylic acid（free acid）
    Vari Fluor 488 Carboxylic acid (VF 488 Carboxylic acid) free acid is a carboxylic acid derivative of Vari Fluor. Vari Fluor carboxylic acid derivatives are unactivated labeled fluorescent dyes for protein, antibody, and polysaccharide labeling that require carboxylic acid activation for use.
    Vari Fluor 488 Carboxylic acid（free acid）
  • HY-135635
    ABL-001-Amide-PEG3-acid
    ABL-001-Amide-PEG3-acid, an analogue of ABL-001, is usually used as a labeled chemical or fluorescent probe.
    ABL-001-Amide-PEG3-acid
  • HY-138660
    HM Janelia Fluor® 526, SE
    HM Janelia Fluor® 526, SE (HM-JF526 NHS) is a derivative of hydroxymethyl JF526 (HM-JF526). SMLM (single-molecule localization microscopy) imaging in standard phosphate-buffered saline (pH 7.4) revealed that the HM-JF526 label showed spontaneous blinking behavior throughout the imaging session and did not require short-wavelength activation light. Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    HM Janelia Fluor® 526, SE
  • HY-D1678
    5(6)-Carboxynaphthofluorescein diacetate
    5(6)-Carboxynaphthofluorescein diacetate is a fluorescent substrate for esterase assays that can be cleaved by intracellular esterases, producing red fluorescence to measure enzyme activity (Ex = 590 nm; Em = 645 nm).
    5(6)-Carboxynaphthofluorescein diacetate
  • HY-D1326
    Cyanine3 carboxylic acid
    Cyanine3 carboxylic acid belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
    Cyanine3 carboxylic acid
  • HY-D2931
    SNAP-FAM
    SNAP-FAM is a FAM-labeled SNAP tag fluorescent probe, specifically designed for live-cell protein labeling and real-time imaging applications.
    SNAP-FAM
  • HY-D2204
    SHP1-IN-1
    SHP1-IN-1 (compound 5p) is a fluorescent probe for the protein tyrosine phosphatase SHP1 containing the Src homology 2 domain. SHP1-IN-1 has SHP1 inhibitory activity, selectivity for Fe3+ ions and good fluorescence properties. SHP1-IN-1 exhibits aggregation post-quenching (ACQ) effect, good interference immunity and low detection limit (5.55 μM).
    SHP1-IN-1
  • HY-D0485
    Fluorescent brightener 24
    Fluorescent brightener 24 is a stilbene-type fluorescent brightener and fading regulator.
    Fluorescent brightener 24
  • HY-NP218
    NP-APC (Allophycocyanin)
    NP-APC (Allophycocyanin) is a conjugate that links NP (a hapten) and APC (fluorescent protein) together. NP-APC (Allophycocyanin) is used in immunological research as a tool for specifically labeling cells and antibodies (Ex/Em = 650/660 nm).
    NP-APC (Allophycocyanin)
  • HY-D1851
    Trisulfo-Cy3 amine disodium
    Cy3B amine chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group in the disodium salt form. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
    Trisulfo-Cy3 amine disodium
  • HY-D0290
    Quinoline yellow 2SF
    Quinoline yellow 2SF is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Quinoline yellow 2SF
  • HY-135634
    GNF-2-PEG-acid
    GNF-2-PEG-acid, an analogue of GNF-2, is usually used as a labeled chemical or fluorescent probe.
    GNF-2-PEG-acid
  • HY-W998694
    6-CR, 6G
    6-CR, 6G is an acceptor chromophore commonly used in energy transfer (ET) fluorescent primers.
    6-CR, 6G
  • HY-D1471
    10-(3-Sulfopropyl)acridinium Betaine
    10-(3-Sulfopropyl)acridinium Betaine is a fluorescent dye with high durability (>3 months).
    10-(3-Sulfopropyl)acridinium Betaine
  • HY-D1822
    Vari Fluor 555 Carboxylic acid（free acid）
    Vari Fluor 555 Carboxylic acid (VF 555 Carboxylic acid) free acid is a carboxylic acid derivative of Vari Fluor. Vari Fluor carboxylic acid derivatives are unactivated labeled fluorescent dyes for protein, antibody, and polysaccharide labeling that require carboxylic acid activation for use.
    Vari Fluor 555 Carboxylic acid（free acid）
Cat. No. Product Name / Synonyms Application Reactivity