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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D2670
    Cy5.5 HA biotin 5000
    Cy5.5 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY5.5 (HY-D0924). Cy5.5 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 680/710 nm).
    Cy5.5 HA biotin 5000
  • HY-D0727
    Pigment yellow 174
    Pigment yellow 174 is a disazomethine dye with solid-state fluorescence.a biologically active chemical.
    Pigment yellow 174
  • HY-D0820A
    CY5-YNE triethylamine
    CY5-YNE (Sulfo-Cyanine5-alkyne) triethylamine is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides (Ex: 650 nM; Em: 680 nm). CY5-YNE triethylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CY5-YNE triethylamine
  • HY-D1337
    Cyanine7 carboxylic acid chloride
    Cyanine7 carboxylic acid chloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
    Cyanine7 carboxylic acid chloride
  • HY-D0105
    Fluorescein diacetate 6-isothiocyanate
    Fluorescein diacetate 6-isothiocyanate is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
    Fluorescein diacetate 6-isothiocyanate
  • HY-134311
    8-NBD-cGMP
    8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I α and I β. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites
    8-NBD-cGMP
  • HY-W281713
    3,6-Dichlorofluorescein
    3,6-Dichlorofluorescein, a fluoresceina, can be used in the spot test for drugs containing amino and heterocyclic nitrogen.
    3,6-Dichlorofluorescein
  • HY-D2710
    Cy3 Dextran (MW 40000)
    Cy3 Dextran (MW 40000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Dextran (HY-112624). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Dextran has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander (Ex/Em = 550/570 nm).
    Cy3 Dextran (MW 40000)
  • HY-D2858
    8-arm-PEG10000-FITC
    8-Arm-PEG10000-FITC is a fluorescent dye composed of FITC (HY-66019) and eight-arm polyethylene glycol (8-Arm PEG). 8-Arm-PEG10000-FITC can be used to modify proteins, peptides and other materials with active groups (Ex/Em=488/525 nm).
    8-arm-PEG10000-FITC
  • HY-D2291
    BODIPY TMR NHS ester
    BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    BODIPY TMR NHS ester
  • HY-D2614
    ICG PEG2000 biotin
    ICG PEG2000 biotin is a fluorescent dye composed of Indocyanine green (ICG) (HY-D0711), PEG and biotin. Indocyanine green provides it with fluorescent labeling function, PEG enhances its biocompatibility and stability, and biotin can bind to target molecules containing streptavidin to achieve targeted imaging or targeted delivery (Ex/Em=785/813 nm).
    ICG PEG2000 biotin
  • HY-D2745
    BP Fluor 594 NHS ester
    BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection. BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.
    BP Fluor 594 NHS ester
  • HY-137592A
    Nicotinamide 1,N6-ethenoadenine dinucleotide sodium
    Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) sodium, a fluorescent analogue of NAD, is able to serve as a substrate for the bacterial toxincatalyzed G-ADP ribosylation of signal-transducing G-proteins. Nicotinamide 1,N6-ethenoadenine dinucleotide sodium can be used as a fluorescent substrate for the studies of the ADP ribosylation reaction.
    Nicotinamide 1,N6-ethenoadenine dinucleotide sodium
  • HY-D1316
    Cyanine7 azide chloride
    Cyanine7 azide chloride belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
    Cyanine7 azide chloride
  • HY-158741
    IPG-2 AM
    IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics.
    IPG-2 AM
  • HY-D2655
    Cy5 HA biotin 10000
    Cy5 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 633/670 nm).
    Cy5 HA biotin 10000
  • HY-D0539
    Direct red 239
    Direct red 239 is a good dyeing agent for cotton fabrics.
    Direct red 239
  • HY-D0399
    C.I. Acid blue 40
    C.I. Acid blue 40 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    C.I. Acid blue 40
  • HY-D0653
    Reactive orange 35
    Reactive orange 35 is common textile dyes that can be adsorbed onto single-walled carbon nanotubes (SWCNTs) through electrostatic interactions, allowing the separation of residual dyes.
    Reactive orange 35
  • HY-D2497
    Sulfo Cy7 bis-SH
    Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Sulfo Cy7 bis-SH
Cat. No. Product Name / Synonyms Application Reactivity