IPG-2 AM
IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics.
For research use only. We do not sell to patients.
- CAS No.: 1369302-24-8
- Formula: C55H64Cl2N2O19
- Molecular Weight:1128.00
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IPG-2 AM (1 μM; 10 min at 37°C) enables quantitative detection of intracellular potassium concentration changes in J774A.1 macrophages and BMDMs exposed to nsPEFs, and can detect immediate potassium efflux and subsequent recovery processes in most treated cell populations[1].
Real-time flow cytometry analysis monitors cytoplasmic potassium efflux in human platelets treated with IPG-2 AM (0.1 μM; 60 min)[2].
IPG-2 AM (0.1 μM; 60 min) exhibits an apparent Kd of 31 mM in human platelets, which validates its suitability for the quantitative detection of cytoplasmic potassium concentrations[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1369302-24-8
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Molecular Weight 1128.00
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Formula C55H64Cl2N2O19
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SMILES
O=C(C)OCOC(CCC1=CC2=C(C3=CC(OC)=C(N4CCOCCOCCN(CCOCCOCC4)C5=CC=C(C)C=C5OC)C=C3)C6=C(C(Cl)=C(C(CCC(OCOC(C)=O)=O)=C6)OCOC(C)=O)OC2=C(C1=O)Cl)=O
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Synonyms
APG-2 Acetoxymethyl ester
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IPG-2 AM Related Classifications
HY-158741 Related Classifications
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