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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W338294S1
    2'-Deoxycytidine-13C-2 monohydrate
    2'-Deoxycytidine-13C-2 (monohydrate) Monohydrate is the 13C labeled 2'-Deoxycytidine.
    2'-Deoxycytidine-<sup>13</sup>C-2 monohydrate
  • HY-116028S1
    15-deoxy-Δ12,14-Prostaglandin D2-d4
    15-Deoxy-Δ12,14-Prostaglandin D2-d4 (15-Deoxy-Δ12,14-PGD2-d4) is the deuterium labeled 15-deoxy-Δ12,14-Prostaglandin D2. 15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2) is a metabolite of prostaglandin D₂ (PGD₂) (HY-101988), which can undergo further dehydration metabolism to 15-deoxy-Δ12,14-PGJ₂. 15-deoxy-Δ12,14-Prostaglandin D2 is a highly selective agonist for DP2 receptor and PPARγ. 15-deoxy-Δ12,14-Prostaglandin D2 causes morphological changes in eosinophils and migration of type II innate lymphoid cells (ILC2). 15-deoxy-Δ12,14-Prostaglandin D2 has a growth inhibitory effect on prostate cancer cells expressing PPARγ, induces cell cycle arrest and promotes apoptosis. 15-deoxy-Δ12,14-Prostaglandin D2 can be used in related research on asthma and prostate cancer.
    15-deoxy-Δ12,14-Prostaglandin D2-d<sub>4</sub>
  • HY-P2625S
    GLP-2(3-33) (Leu-13C6,15N)
    GLP-2(3-33) (Leu-13C6,15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
    GLP-2(3-33) (Leu-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N)
  • HY-W716464
    Prochloraz-d7
    Prochloraz-d7 (BTS 40542-d7) is the deuterium labeled Prochloraz (HY-B0845). Prochloraz is an imidazole antifungal. Prochloraz is as an estrogen receptor (ER) and androgen receptor (AR) antagonist and an aromatase inhibitor with IC50 values of 25 μM, 4 μM and 0.3 μM, respectively. Prochloraz is able to activate the aryl hydrocarbon receptor (AhR) having an EC50 of 1 μM.
    Prochloraz-d<sub>7</sub>
  • HY-W751468
    3,5-O-Dibenzyl Metaproterenol-d7
    3,5-O-Dibenzyl Metaproterenol-d7 is the deuterium labeled 3,5-O-Dibenzyl Metaproterenol.
    3,5-O-Dibenzyl Metaproterenol-d<sub>7</sub>
  • HY-176349S
    HRAS, Arg-13C6,15N4, Lys-13C6,15N2
    HRAS, Arg-13C36, 15N4, Lys-13C6, 15N2 is the 13C- and 15N-labeled HRAS.
    HRAS, Arg-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>4</sub>, Lys-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-122217S
    Pyridate-d5
    Pyridate-d5 is deuterium labeled Pyridate.
    Pyridate-d<sub>5</sub>
  • HY-150994S
    2-Methoxy-3,5-dimethylpyrazine-d3
    2-Methoxy-3,5-dimethylpyrazine-d3 is the deuterium labeled 2-Methoxy-3,5-dimethylpyrazine.
    2-Methoxy-3,5-dimethylpyrazine-d<sub>3</sub>
  • HY-W721134
    N-(2,4-Dimethylphenyl)formamide-d9
    N-(2,4-Dimethylphenyl)formamide-d9 is the deuterium labeled N-(2,4-Dimethylphenyl)formamide (HY-W013655).
    N-(2,4-Dimethylphenyl)formamide-d<sub>9</sub>
  • HY-W342458S
    Betamethasone 17-propionate-d4
    Betamethasone 17-propionate-d4 is the deuterium labeled Betamethasone 17-propionate.
    Betamethasone 17-propionate-d<sub>4</sub>
  • HY-B0966S
    Dioxybenzone-d3
    Dioxybenzone-d3 is deuterium labeled Dioxybenzone. Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study.
    Dioxybenzone-d<sub>3</sub>
  • HY-N7101S
    Cefpodoxime proxetil-d7
    Cefpodoxime proxetil-d7 (U-76-d7,252-d7; CS-807-d7) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases.
    Cefpodoxime proxetil-d<sub>7</sub>
  • HY-N3686S2
    D-Arabitol-13C-2
    D-Arabitol-13C-2 is the 13C labeled D-Arabitol. D-Arabitol is an orally active D-enantiomer of arabitol. D-Arabitol modulates the composition of gut microbiota, increases short-chain fatty acids, and promotes AMPK-PGC-1α-related browning of white adipose tissue. D-Arabitol improves weight gain, fat accumulation, insulin resistance, lipid deposition and inflammatory responses. D-Arabitol serves as the sole carbon/energy source for Bacillus methanolicus MGA3, a strain that can co-utilize it with mannitol. D-Arabitol is applicable to obesity-related research.
    D-Arabitol-<sup>13</sup>C-2
  • HY-B0887S1
    Permethrin-d9
    98.20%
    Permethrin-d9 is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation.
    Permethrin-d<sub>9</sub>
  • HY-143957S
    Fenretinide glucuronide-d4
    Fenretinide glucuronide-d4 is the deuterium labeled Fenretinide glucuronide.
    Fenretinide glucuronide-d<sub>4</sub>
  • HY-W110705S1
    1-Bromopentadecane-d31
    1-Bromopentadecane-d31 is the deuterium labeled 1-Bromopentadecane.
    1-Bromopentadecane-d<sub>31</sub>
  • HY-127025S1
    8-Hydroxy loxapine-d8
    8-Hydroxy loxapine-d8 is the deuterium labeled 8-Hydroxy loxapine (HY-127025). 8-Hydroxy loxapine is the relatively inactive oxidative metabolite of Loxapine (HY-17390), compared to 7-OH-loxapine.
    8-Hydroxy loxapine-d<sub>8</sub>
  • HY-W766046
    2'-Deoxy-3',5'-di-O-p-toluoyl Uridine-13C,15N2
    2'-Deoxy-3',5'-di-O-p-toluoyl Uridine-13C,15N2 is the 13C- and 15N-labeled 2'-Deoxy-3',5'-di-O-p-toluoyl Uridine.
    2'-Deoxy-3',5'-di-O-p-toluoyl Uridine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-112823S
    Almonertinib-d6
    Almonertinib-d6 (HS-10296-d6) is the deuterium labeled Almonertinib (HY-112823). Almonertinib (HS-10296) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib is used for the research of the non-small cell lung cancer.
    Almonertinib-d<sub>6</sub>
  • HY-W704306
    N-Methyl mepivacaine-d6 iodide
    N-Methyl mepivacaine-d6 iodide is the deuterium labeled N-Methyl mepivacaine iodide.
    N-Methyl mepivacaine-d<sub>6</sub> iodide