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  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds 関連製品 (10876):

製品番号 製品名 製品効果 純度 構造式
  • HY-W007941S1
    Fmoc-Ser(tBu)-OH-15N 99.8%
    Fmoc-Ser(tBu)-OH-15N is the 15N labeled Fmoc-Ser(tBu)-OH. Fmoc-Ser(tBu)-OH is a serine derivative.
    Fmoc-Ser(tBu)-OH-<sup>15</sup>N
  • HY-B1381S
    Cefixime-13C,15N2
    Cefixime-13C,15N2 (FR-17027-13C,15N2) is the 13C- and 15N-labeled Cefixime (HY-B1381). Cefixime (FR-17027) is an orally active antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.
    Cefixime-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-10224S1
    Panobinostat-d4 hydrochloride
    Panobinostat-d4 (hydrochloride) is deuterium labeled Panobinostat. Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3].
    Panobinostat-d<sub>4</sub> hydrochloride
  • HY-W738684
    Biuret-15N3
    Biuret-15N3 is the 15N labeled Biuret (HY-W015927).
    Biuret-<sup>15</sup>N<sub>3</sub>
  • HY-109120S1
    Odevixibat-13C6
    Odevixibat-13C6 is 13C labeled Odevixibat (HY-109120). Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis.
    Odevixibat-<sup>13</sup>C<sub>6</sub>
  • HY-W723937
    1-Bromopentadecane-d4
    1-Bromopentadecane-d4 (Pentadecyl bromide-d4) is the deuterium labeled 1-Bromopentadecane.
    1-Bromopentadecane-d<sub>4</sub>
  • HY-16781S
    Grapiprant-d4
    Grapiprant-d4 (CJ-023423-d4) is the deuterium labeled Grapiprant (HY-16781). Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment[3] .
    Grapiprant-d<sub>4</sub>
  • HY-136456S
    2-NP-AMOZ-d5
    2-NP-AMOZ-d5 is deuterium labeled 2-NP-AMOZ. 2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ (a metabolite of antibiotic Furaltadone), can be used to detect protein bound AMOZ.
    2-NP-AMOZ-d<sub>5</sub>
  • HY-W707595
    O-tert-Butyl-2-hydroxy efavirenz-d5
    O-tert-Butyl-2-hydroxy efavirenz-d5 is the deuterium labeled O-tert-Butyl-2-hydroxy Efavirenz (HY-W744274).
    O-tert-Butyl-2-hydroxy efavirenz-d<sub>5</sub>
  • HY-W654234
    Hydroxyphenyllactic acid-d3
    Hydroxyphenyllactic acid-d3 is the deuterium labeled Hydroxyphenyllactic acid (HY-113219). Hydroxyphenyllactic acid is an antifungal metabolite.
    Hydroxyphenyllactic acid-d<sub>3</sub>
  • HY-W020018S2
    N-Methylacetamide-d3
    N-Methylacetamide-d3 is the deuterium labeled N-Methylacetamide.
    N-Methylacetamide-d<sub>3</sub>
  • HY-166608S
    N2-Acetyl acyclovir benzoate-d4
    N2-Acetyl acyclovir benzoate-d4 is the deuterium labeled N2-Acetyl acyclovir benzoate.
    N2-Acetyl acyclovir benzoate-d<sub>4</sub>
  • HY-I0717S
    1-Acetylnaphthalene-d3 98.9%
    1-Acetylnaphthalene-d3 is the deuterium labeled 1-Acetylnaphthalene.
    1-Acetylnaphthalene-d<sub>3</sub>
  • HY-W710423S
    3,5-Diamino-4-chlorobenzonitrile-15N2
    3,5-Diamino-4-chlorobenzonitrile-15N2-1 is the 15N-labeled 3,5-Diamino-4-chlorobenzonitrile (HY-W710423).
    3,5-Diamino-4-chlorobenzonitrile-<sup>15</sup>N<sub>2</sub>
  • HY-W013027S
    2-Amino-2-methyl-1-propanol-d11
    2-Amino-2-methyl-1-propanol-d11 is the deuterium labeled 2-Amino-2-methyl-1-propanol.
    2-Amino-2-methyl-1-propanol-d<sub>11</sub>
  • HY-B0623S
    Ropinirole-d14
    Ropinirole-d14 is the deuterium labeled Ropinirole.
    Ropinirole-d<sub>14</sub>
  • HY-N0215S9
    L-Phenylalanine-13C9,15N,d8
    L-Phenylalanine-13C9,15N,d8 is the deuterium, 13C-, and 15-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
    L-Phenylalanine-<sup>13</sup>C<sub>9</sub>,<sup>15</sup>N,d<sub>8</sub>
  • HY-19717S
    DCVC-13C3,15N
    DCVC-13C3,15N is 15N and 13C labeled DCVC. DCVC (S-[(1E)-1,2-Dichloroethenyl]-L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-α release from tissue cultures.
    DCVC-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N
  • HY-W751756
    6-Cyano Diclazuril-13C3,15N2
    6-Cyano Diclazuril-13C3,15N2 is the 13C- and 15N-labeled 6-Cyano Diclazuril.
    6-Cyano Diclazuril-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-B2046S
    Simazine-d10
    Simazine-d10 is the deuterium labeled Simazine (HY-B2046). Simazine is a triazine herbicide. Simazine is widely used in agriculture, potted plant and tree production. In addition, Simazine can induce the apoptosis of immune cells in the spleen of mice and inhibit the proliferation of B cells and T cells in mice.
    Simazine-d<sub>10</sub>