Grapiprant-d4
Grapiprant-d4 (CJ-023423-d4) is the deuterium labeled Grapiprant (HY-16781). Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment[3] .
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C26H25D4N5O3S
- Molecular Weight:495.63
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 415903-37-6
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Molecular Weight 495.63
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Formel C26H25D4N5O3S
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SMILES
O=S(C1=CC=C(C)C=C1)(NC(NC([2H])([2H])C([2H])([2H])C2=CC=C(N3C(CC)=NC4=C3C=C(C)N=C4C)C=C2)=O)=O
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Synonyms
CJ-023423-d4; RQ-00000007-d4; AAT-007-d4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Grapiprant-d4 Related Classifications
HY-16781S Related Classifications
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