Cefixime-13C,15N2
Cefixime-13C,15N2 (FR-17027-13C,15N2) is the 13C- and 15N-labeled Cefixime (HY-B1381). Cefixime (FR-17027) is an orally active antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.
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- Formule: C1513CH15N315N2O7S2
- Masse moléculaire:456.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | IC50 |
10 mM
Compound: Cefixime
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TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 5 uM) in Caco-2 cells
TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 5 uM) in Caco-2 cells
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[PMID: 9092716] |
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 79350-37-1
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Masse moléculaire 456.43
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Formule C1513CH15N315N2O7S2
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SMILES
O=C(O)C(N1[C@@]([H])([C@@H](C1=O)NC(/C(C2=CS[13C]([15NH2])=[15N]2)=N\OCC(O)=O)=O)SC3)=C3C=C
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Synonyms
FR-17027-13C,15N2 ; FK-027-13C,15N2 ; CL-284635-13C,15N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)