Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10873):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-109523S

Cerivastatin-d₃ sodium
Cerivastatin-d₃ sodium is deuterated labeled Cerivastatin sodium (HY-109523). Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin sodium reduces low-density lipoprotein cholesterol levels. Cerivastatin sodium also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect.

HY-W698694

N4-Acetylsulfamerazine-d₄
N4-Acetylsulfamerazine-d₄ (Acetylsulfamerazine-d₄; Sulfamelazine-d₄) is the deuterium labeled N4-Acetylsulfamerazine (HY-W031230). N4-Acetylsulfamerazine is a sulfonamides derivative.

HY-W069721S1

N-Acetylsulfanilamide-¹³C₆
N-Acetylsulfanilamide-¹³C₆ is the ¹³C₆ labeled N-Acetylsulfanilamide.

HY-Y0658S

Tetramethyl-ammonium Bromide-d₁₂
Tetramethyl-ammonium Bromide-d₁₂ is the deuterium labeled TMAB.

HY-138586S

DMT-dC(ac) Phosphoramidite-¹³C₉, ¹⁵N₃
DMT-dC(ac) Phosphoramidite-¹³C₉, ¹⁵N₃ is the ¹³C- and ¹⁵N-labeled DMT-dC(ac) Phosphoramidite (HY-138586). DMT-dC(ac) Phosphoramidite (compound 30f) is a phosphoramidite derivative that can be used for the oligonucleotide synthesis.

HY-W008566S

Norharmane-¹³C
Norharmane-¹³C (Norharman-¹³C) is the ¹³C-labeled Norharmane (HY-W008566). Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings.

HY-W702983

Desamino glufosinate-d₃
Desamino glufosinate-d₃ is the deuterium labeled Desamino glufosinate.

HY-146891S

DPPC-d₃₁
16:0-16:0 PC-d₃₁ is deuterium labeled 16:0-16:0 PC.

HY-143963S

Irbesartan impurity 20-d₄
Irbesartan impurity 20-d₄ is the deuterium labeled Irbesartan impurity 20. Irbesartan impurity 20-d₄ is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W778179

Benoxaprofen-¹³C,d₃
Benoxaprofen-¹³C, d₃ is the ¹³C-labeled Benoxaprofen (HY-13568). Benoxaprofen (LRCL 3794) is a nonsteroidal anti-inflammatory agent that blocks the biosynthesis of inflammatory mediators such as leukotrienes and prostaglandins by inhibiting 5-LOX, PGH2 synthase and cytochrome P-450. Benoxaprofen exhibits significant toxicity: it not only alters cellular redox status, uncouples oxidative phosphorylation and disrupts calcium ion homeostasis, but also causes liver injury through the formation of covalent adducts between its active metabolites and hepatic proteins. Benoxaprofen shows strong phototoxicity under ultraviolet irradiation, and induces erythrocyte lysis, mast cell degranulation and histamine release. Benoxaprofen is widely used in studies of urticaria and related phototoxic mechanisms.

HY-151068S

2,3′,4′,5-Tetrachlorobiphenyl-3,4,6-d₃
2,3′,4′,5-Tetrachlorobiphenyl-3,4,6-d₃ is the deuterium labeled 2,3′,4′,5-Tetrachlorobiphenyl.

HY-Y1275S1

N-Methylpyrrolidone-d₃
N-Methylpyrrolidone-d₃ is the deuterium labeled N-Methylpyrrolidone . N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone), a five-membered cyclic amide, is an organic polar solvent. N-Methylpyrrolidone is extensively used in the manufacture of adhesives, paints, fuels, and pharmaceuticals.

HY-166889S

2,4,5-Trichloro-4'-methoxy-biphenyl-C¹³C₁₂
2,4,5-Trichloro-4'-methoxy-biphenyl-¹³C₁₂ is ¹³C labeled 2,4,5-Trichloro-4'-methoxy-biphenyl.

HY-W710279

N-ethyl-N-oxido-dodecan-1-amine-d₆
N-ethyl-N-oxido-dodecan-1-amine-d₆ is the deuterium labeled N-ethyl-N-oxido-dodecan-1-amine (HY-W127785). N-ethyl-N-oxido-dodecan-1-amine is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.

HY-B0674S

Ebastine-d₅
Ebastine-d₅ is the deuterium labeled Ebastine. Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research.

HY-143980S

Losartan impurity 21-d₄
Losartan impurity 21-d₄ is the deuterium labeled Losartan impurity 21. Losartan impurity 21-d4 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-B1658CS

ent-Frovatriptan-d₃ succinate
ent-Frovatriptan-d₃ (succinate) is deuterium labeled ent-Frovatriptan.

HY-W013068S3

DMT-dT Phosphoramidite-d₁₁
DMT-dT Phosphoramidite-d₁₁ is deuterium labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.

HY-W705455

3-Nitrobiphenyl-d₉
3-Nitrobiphenyl-d₉ is the deuterium labeled 3-Nitrobiphenyl (HY-W150434).

HY-W008034S

Fmoc-Trp(Boc)-OH-¹³C₁₁,¹⁵N₂
Fmoc-Trp(Boc)-OH-¹³C₁₁,¹⁵N₂ (Fmoc-L-Trp(Boc)-OH-¹³C₁₁,¹⁵N₂) is the ¹³C-labeled and ¹⁵N-labeled Fmoc-Trp(Boc)-OH (HY-W008034). Fmoc-Trp(Boc)-OH (Fmoc-L-Trp(Boc)-OH) is an amino acid derivative with protective groups. Fmoc-Trp(Boc)-OH can self-assemble into stable and pH-responsive spherical nanoparticles, which can load and release bioactive molecules, with good biocompatibility and high cell uptake rate. Fmoc-Trp(Boc)-OH can be used in research on drug delivery.

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