Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W699735

(E)-2-Methylbut-2-enoic-4,4,4-d₃ acid
(E)-2-Methylbut-2-enoic-4,4,4-d₃ acid is the deuterium labeled Tiglic acid (HY-W012999). Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite.

HY-30235S

Benzydamine-d₆ hydrochloride
Benzydamine-d6 hydrochloride is the deuterium labeled Benzydamine hydrochloride.

HY-W752483

Hydrocortisone 21-Acetate-d₃
Hydrocortisone 21-Acetate-d₃ is the deuterium labeled Hydrocortisone 21-Acetate.

HY-B0252S3

Hydrochlorothiazide-¹⁵N₂,¹³C,d₂
Hydrochlorothiazide-¹⁵N₂,¹³C,d₂ is ¹⁵N and deuterated labeled Hydrochlorothiazide (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect.

HY-W743473

Cefetamet-d₃
Cefetamet-d₃ (Ro 15-8074-d₃; Deacetoxycefotaxime-d₃) is the deuterium labeled Cefetamet (HY-A0111). Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC₅₀ for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis.

HY-13286S

N-Hydroxy (E)-2-(4-methoxybenzoxy)-4-methoxy-3-prenylcinnamamide-d₆
N-Hydroxy (E)-2-(4-methoxybenzoxy)-4-methoxy-3-prenylcinnamamide-d₆ is the deuterium labeled N-Hydroxy (E)-2-(4-methoxybenzoxy)-4-methoxy-3-prenylcinnamamide.

HY-W654058

L-Arginine-¹³C,d₄(dihydrochloride)
L-Arginine-¹³C,d₄ (dihydrochloride) is ¹³C labeled L-Arginine (dihydrochloride).

HY-N0658S2

L-Threonine-¹³C₄,¹⁵N,d₅
L-Threonine-¹³C₄,¹⁵N,d₅ is the deuterium, ¹³C-, and 15-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed.

HY-B0274CS

(E/Z)-Chlorprothixene-d₆ hydrochloride
(E/Z)-Chlorprothixene-d₆ hydrochloride is the deuterium labeled (E/Z)-Chlorprothixene hydrochloride.

HY-135810S1

Cletoquine-d₄-1
Cletoquine-d₄-1 is the deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment.

HY-B1845S

Florasulam-¹³C,d₃
Florasulam-¹³C,d₃ is the ¹³C- and deuterium labeled Florasulam.

HY-W753976

Ethyl chrysanthemate-d₆
Ethyl chrysanthemate-d₆ is the deuterium labeled Ethyl chrysanthemate (HY-N7100). Ethyl chrysanthemate is an allelochemical compound used as an attractant.

HY-17372S

Rofecoxib-d₅
Rofecoxib-d₅ is the deuterium labeled Rofecoxib. Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC₅₀s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC₅₀ > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells).

HY-B0104S1

Glimepiride-d₄-1		99.39%
Glimepiride-d₄-1 is deuterium labeled Glimepiride. Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.

HY-N0215S16

L-Phenylalanine-¹³C-1
L-Phenylalanine-¹³C-1 ((S)-2-Amino-3-phenylpropionic acid-¹³C-1) is the ¹³C-labeled L-Phenylalanine (HY-N0215). L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca²⁺ channels antagonist with a K_i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (K_b of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.

HY-145476S2

N-Nitrosoanatabine-d₃
N-Nitrosoanatabine-d₃ (N-NAT-d₃) is the deuterium labeled N-Nitrosoanatabine (HY-145476). (R,S)-N-Nitrosoanatabine (N-NAT) is a tobacco-specific nitrosamine (TSNA) that has been found in tobacco, tobacco products, and electronic cigarettes. The (S) enantiomer comprises approximately 80% of the N-NAT found in commercial and research cigarettes and smokeless tobacco.3 Unlike other TSNAs, N-NAT is not carcinogenic in rats when administered at doses of 1, 3, and 9 mmol/kg.

HY-B0178AS2

Guanidine-¹³C hydrochloride
Guanidine-¹³C hydrochloride (Guanidinium-¹³C chloride) is the ¹³C-labeled Guanidine hydrochloride (HY-B0178A). Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins.

HY-W013061S6

Propane-1,2,3-triyl tripalmitate-d₉₈
Propane-1,2,3-triyl tripalmitate-d₉₈ is the deuterium labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035).

HY-W712932

Chenodeoxycholic Acid-d₇
Chenodeoxycholic Acid-d₇ (CDCA-d₇) is the deuterium labeled Chenodeoxycholic Acid (HY-76847). Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

HY-W101495S3

Boc-Leu-OH·H2O-d₇
Boc-Leu-OH·H2O-d₇ is the deuterium labeled Boc-Leu-OH·H2O.

Name
Email *

	Sorry, but the email address you supplied was invalid.