Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Verwandte Produkte (10876):

Art. -Nr.	Produktname	Wirkung	Reinheit	Chemical Structure

HY-N0667S7

L-Asparagine-¹³C₄,¹⁵N₂
L-Asparagine-¹³C₄,¹⁵N₂ ((-)-Asparagine-¹³C₄,¹⁵N₂) is the ¹³C and ¹⁵N-labeled L-Asparagine (HY-N0667). L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.

HY-146659S

S-Phenyl-DL-cysteine-d₂
S-Phenyl-DL-cysteine-3,3-d₂ is the deuterium labeled S-Phenyl-DL-cysteine-3,3.

HY-W141919S

(±)-N-(2-Methylbutyryl)glycine-2,2-d₂
(±)-N-(2-Methylbutyryl)glycine-2,2-d₂ is the deuterium labeled (±)-N-(2-Methylbutyryl)glycine-2,2.

HY-B0116S

Stavudine-d₄
Stavudine-d₄ is the deuterium labeled Stavudine. Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis.

HY-13295S

Vinpocetine-d₅
Vinpocetine-d₅ is the deuterium labeled Vinpocetine. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC₅₀ value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders.

HY-W741345

DL-threo-Ritalinic Acid-d₁₀
DL-threo-Ritalinic Acid-d₁₀ is the deuterium labeled (R)-2-phenyl-2-((R)-piperidin-2-yl)acetic acid (HY-W422491).

HY-W769158

9,10-Dehydro Folitixorin-(phenylene-d₄) Chloride
9,10-Dehydro Folitixorin-(phenylene-d₄) Chloride is the deuterium labeled 9,10-Dehydro Folitixorin-(phenylene) Chloride .

HY-W741976

6-Methylthioguanine-d₃
6-Methylthioguanine-d₃ (6-(Methylsulfanyl)-7h-purin-2-amine-d₃) is the deuterium labeled 6-(Methylsulfanyl)-7h-purin-2-amine (HY-W198678).

HY-22306S

β-D-Glucose pentaacetate-¹³C₆
β-D-Glucose pentaacetate-¹³C₆ is the ¹³C labeled β-D-Glucose pentaacetate[1]. β-D-Glucose Pentaacetate (Penta-O-acetyl-β-D-glucopyranose) is used in biochemical reaction.

HY-B0716S2

Urapidil-d₄
Urapidil-d₄ is the deuterium labeled Urapidil. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.

HY-W777281

Fluocinolone acetonide-¹³C₃
Fluocinolone acetonide-¹³C₃ is the ¹³C-labeled Fluocinolone (Acetonide) (HY-B0415). Fluocinolone is a glucocorticoid glucocorticoid receptor agonist. Fluocinolone is effective in preventing both lipid accumulation and inflammation. Fluocinolone can promote the proliferation of DPCs and has the potential role in repairing injured pulp tissues. Fluocinolone can be used to study the prevention of chemotherapy-induced peripheral neuropathy caused by Paclitaxel (HY-B0015).

HY-W777759

6-Amino-5-nitroso-2-thiouracil-¹³C,¹⁵N
6-Amino-5-nitroso-2-thiouracil-¹³C,¹⁵N (4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine-¹³C,¹⁵N) is the ¹³C- and ¹⁵N-labeled 6-Amino-5-nitroso-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (HY-75602).

HY-W243217

Acetamide-d₃		98.0%
Acetamide-2,2,2-d₃ is the deuterium labeled Acetamide-2,2,2-d₃.

HY-150931S

Uridine 5'-triphosphate (UTP)-d₅ tetraammonium
Uridine 5'-triphosphate (UTP)-d₅ (tetraammonium) is the deuterium labeled Uridine 5'-triphosphate (UTP) tetraammonium.

HY-W700119

1-(4-Chlorobenzhydryl)piperazine-d₈
1-(4-Chlorobenzhydryl)piperazine-d₈ is the deuterium labeled 1-(4-Chlorobenzhydryl)piperazine (HY-W001978). 1-(4-Chlorobenzhydryl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-124265S1

4β-Hydroxycholesterol-d₅
4β-Hydroxycholesterol-d₅ is the deuterium labeled 4β-Hydroxycholesterol (HY-124265). 4β-Hydroxycholesterol is a major Cholesterol (HY-N0322) metabolite and a precursor in the synthesis of bile acids that is found in human circulation.

HY-W724381

Ethyl decanoate-d₁₉
Ethyl decanoate-d₁₉ (Decanoic Acid Ethyl Ester-d₁₉) is the deuterium labeled Ethyl decanoate (HY-W014884). Ethyl decanoate is an organic compound commonly used as a flavoring and food additive. It can be used to prepare flavors and food seasonings with various flavors, and is widely used in food, flavors and cosmetics. In addition, this compound is also used as a substrate or intermediate in some biochemical reactions.

HY-13600S1

Clobetasol propionate-d₅
Clobetasol propionate-d₅ is a deuterium substitute of Clobetasol propionate. Clobetasol propionate is a potent, selective CYP3A5 inhibitor with a IC₅₀ of 0.206 μM and has potential for use in the study of psoriasis and other skin diseases.

HY-I0230S

Solifenacin-d₇ hydrochloride
Solifenacin-d₇ (hydrochloride) is the deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride (YM905 hydrochloride) is a muscarinic receptor antagonist, with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

HY-W741425

21-O-Acetyl dexamethasone 9,11-epoxide-d₅
21-O-Acetyl dexamethasone 9,11-epoxide-d₅ is the deuterium labeled 2-((4aS,4bS,5aS,6aS,7R,8R,9aS,9bS)-7-Hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,5a,6,6a,7,8,9,9a,9b,10,11-dodecahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-7-yl)-2-oxoethyl acetate (Dexamethasone Acetate Impurity) (HY-Z8003).

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