Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11097)
Related Products (11097)
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Rizatriptan-d6 benzoate
0 ImagesCat. No.: HY-B0206SCAS No.: 1216984-85-8Rizatriptan-d6 (benzoate) is the deuterium labeled Rizatriptan benzoate. Rizatriptan benzoate is the agonist for 5-HT1B and 5-HT1D. Rizatriptan benzoate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system.
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2,3-Diphosphoglyceric acid-d3 ammonium
0 ImagesCat. No.: HY-113050SACAS No.: 2712139-19-8Synonyms: 2,3-DPG-d3 ammonium2,3-Diphosphoglyceric acid-d3 ammonium (2,3-DPG-d3 ammonium) is the deuterium labeled 2,3-Diphosphoglyceric acid (HY-113050). 2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD).
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13,14-Dihydro-15-keto Prostaglandin F2α-d4
0 ImagesCat. No.: HY-113459S1CAS No.: 42932-59-2Synonyms: 13,14-Dihydro-15-keto-PGF2α-d413,14-Dihydro-15-keto Prostaglandin F2α-d4 (13,14-Dihydro-15-keto-PGF2α-d4) is a deuterated labeled 13,14-Dihydro-15-keto Prostaglandin F2α (HY-113208). 13,14-Dihydro-15-keto Prostaglandin F2α-d4 is an endogenous metabolite present in Blood that can be used for the research of Pregnancy.
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3-Hydroxybutanoic acid-13C sodium
0 ImagesCat. No.: HY-W015851SCAS No.: 1173022-79-1Synonyms: 3-Hydroxybutyric acid-13C sodium3-Hydroxybutanoic acid-13C-13C (sodium) is the 13C labeled 3-Hydroxybutanoic acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids.
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Homocarnosine-15N3 TFA
0 ImagesCat. No.: HY-114883BSSynonyms: L-Homocarnosine-15N3 TFAHomocarnosine-15N3 (L-Homocarnosine-15N3) TFA is the 15N-labeled Homocarnosine (HY-114883). Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects.Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation.
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Propane-1,2,3-triyl tripalmitate-13C
0 ImagesCat. No.: HY-W013061S10Propane-1,2,3-triyl tripalmitate-13C is the 13C labeled Propane-1,2,3-triyl tripalmitate (HY-W013061). Propane-1,2,3-triyl tripalmitate is a saturated fat. Propane-1,2,3-triyl tripalmitate enhances the lymphatic transport of Glycerol tristearate (HY-127035).
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1-Bromopentadecane-d3
0 ImagesCat. No.: HY-W110705S3CAS No.: 1219805-83-01-Bromopentadecane-d3 is the deuterium labeled 1-Bromopentadecane.
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[U-15N]-Aβ(1-40)
![[U-15N]-Aβ(1-40)](https://file.medchemexpress.com/product_pic/hy-187189s.gif "Click to View [U-15N]-Aβ(1-40) Product Detail")
0 ImagesCat. No.: HY-187189S[U-15N]-Aβ(1-40) is the 15N-labeled Aβ(1-40). Abnormal levels and aggregation of beta-amyloid (Aβ) in the brain are considered key factors in the pathogenesis of Alzheimer's disease (AD). This isotope can be used in NMR studies of disease mechanisms and in mass spectrometry analysis.
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Danicamtiv-d3
0 ImagesCat. No.: HY-109128S1CAS No.: 2925925-82-0Synonyms: MYK-491-d3Danicamtiv-d3 (MYK-491-d3) is a deuterated labeled Danicamtiv (HY-109128). Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.
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Nitenpyram-d3-1
0 ImagesCat. No.: HY-B0820S1Nitenpyram-d3-1 is the deuterium labeled Nitenpyram (HY-B0820). Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals.
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Chlorhexidine-d8
0 ImagesCat. No.: HY-W738281CAS No.: 1246816-96-5Chlorhexidine-d8 is deuterium-labeled Chlorhexidine (HY-B1248). Chlorhexidine is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis).
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Cyanoguanidine-15N4
0 ImagesCat. No.: HY-W738277CAS No.: 63419-77-2Cyanoguanidine-15N4 is the 15N labeled Dicyandiamide (HY-Y0674).
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Ribitol-5-13C
0 ImagesCat. No.: HY-100582S3Synonyms: Adonitol-5-13C; Adonite-5-13CRibitol-5-13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol-
4-Hydroxyphenylbutazone-d9
0 ImagesCat. No.: HY-W740777CAS No.: 1246819-23-74-Hydroxyphenylbutazone-d9 is the deuterium labeled 4-Hydroxyphenylbutazone (HY-139199). 4-Hydroxyphenylbutazone is a metabolite of Phenylbutazone. Phenylbutazone, a nonsteroidal anti-inflammatory agent (NSAID), is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS).
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Fmoc-Met-OH-13C5,15N
0 ImagesFmoc-Met-OH-13C5,15N is a 15N-labeled and 13C-labled Fmoc-Met-OH (HY-W008371). Fmoc-Met-OH is a Methionine (HY-13694) derivative.
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Propane-1,1,2-d3-1,2-diol
0 ImagesCat. No.: HY-W719128CAS No.: 70195-21-0Propane-1,1,2-d3-1,2-diol is the deuterium labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish.
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2-Amino-4,6-dichloropyrimidine-13C2
0 ImagesCat. No.: HY-W778257CAS No.: 1346605-11-5Synonyms: 4,6-dichloropyrimidin-2-ylamine-13C22-Amino-4,6-dichloropyrimidine-13C2 (4,6-dichloropyrimidin-2-ylamine-13C2) is the 13C-labeled 2-Amino-4,6-dichloropyrimidine (HY-41261).
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Bile acid standards Mix 1-unconjugated
0 ImagesCat. No.: HY-185791SBile acid standards Mix 1-unconjugated is a deuterium-labeled unconjugated bile acid used as an internal standard for quantitative analysis.
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4-tert-Octylphenol monoethoxylate-13C6
0 ImagesCat. No.: HY-W777582CAS No.: 1173019-48-14-tert-Octylphenol monoethoxylate-13C6 is the 13C labeled isotope of 4-tert-Octylphenol monoethoxylate (HY-W777582). 4-tert-Octylphenol monoethoxylate is an alkylphenolethoxylate (APE) and a degradation product of non-ionic surfactants (such as 4-tert-octylphenol polyethoxylate). 4-tert-Octylphenol monoethoxylate also possesses non-steroidal estrogenic activity. Additionally, 4-tert-Octylphenol monoethoxylate has been found in wastewater effluent.
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Cycloguanil-d6 nitrate
0 ImagesCat. No.: HY-12784S1CAS No.: 2070015-19-7Synonyms: Chlorguanide triazine-d6 nitrateCycloguanil-d6 (Chlorguanide triazine-d6) nitrate is the deuterium labeled Cycloguanil nitrate. Cycloguanil nitrate is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 10.8 μM against human DHFR. Cycloguanil nitrate blocks the folate metabolic pathway, thereby affecting nucleotide synthesis and interfering with DNA replication. Cycloguanil nitrate inhibits DHFR in Plasmodium and is thus used in malaria research. Cycloguanil nitrate also potently inhibits DHFR in human cancer cells and blocks the transcriptional activity of STAT3, thereby exhibiting anticancer activity.
