Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W010269S

5-Methoxy-1H-benzo[d]imidazole-d₃
5-Methoxy-1H-benzo[d]imidazole-d₃ is the deuterium labeled 5-Methoxy-1H-benzo[d]imidazole.

HY-W654010

Lurasidone-d₈-1 hydrochloride
Lurasidone-d₈-1 (hydrochloride) is deuterium labeled Lurasidone (Hydrochloride). Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D₂ and 5-HT₇ with IC₅₀s of 1.68 and 0.495 nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is also a partial agonist of 5-HT_1A receptor with an IC₅₀ of 6.75 nM.

HY-41121S6

Boc-L-Ala-OH-d
Boc-L-Ala-OH-d is the deuterium labeled Boc-L-Ala-OH.

HY-N0415S1

Trigonelline-d₃-1 chloride
Trigonelline-d₃-1 chloride (Trigonelline-d₃-1 hydrochloride) is the deuterium labeled Trigonelline chloride (HY-N0415). Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. Trigonelline chloride also has anti-HSV-1, antibacterial, and antifungal activity, and induces ferroptosis.

HY-N0545S2

Taurocholic acid-d₄ sodium
Taurocholic acid-d₄-1 sodium (Sodium taurocholate-d₄-1) is the deuterium labeled Taurocholic acid sodium (HY-N0545). Taurocholic acid sodium (Sodium taurocholate) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid sodium has immunoregulation effect.

HY-W009151S2

Fmoc-Abu-OH-d₅
Fmoc-Abu-OH-d₅ is the deuterium labeled Fmoc-Abu-OH (HY-W009151). Fmoc-Abu-OH is an alanine derivative.

HY-W778137

(S)-(-)-Celiprolol Hydrochloride-d₉
(S)-(-)-Celiprolol Hydrochloride-d₉ is the deuterium labeled (S)-(-)-Celiprolol Hydrochloride (HY-W740762).

HY-W016825S2

2-(Pyridin-2-yl)acetic acid-d₂ hydrochloride
2-(Pyridin-2-yl)acetic acid-d₂ hydrochloride is the deuterated derivative of 2-(Pyridin-2-yl)acetic acid hydrochloride (HY-W016825). 2-(Pyridin-2-yl)acetic acid hydrochloride is a heterocyclic aromatic carboxylic acid compound. 2-(Pyridin-2-yl)acetic acid hydrochloride can be used as an organic synthesis intermediate or a metal complex.

HY-W011222S

1-Bromooctadecane-d₃₇
1-Bromooctadecane-d₃₇ is the deuterium labeled 1-Bromooctadecane.

HY-12142S

rac-Vofopitant-d₃
rac-Vofopitant-d₃ (rac-GR 205171-d₃) is a racemic form of deuterated Vofopitant (HY-12142). Vofopitant (GR 205171A) is a blood-brain barrier-permeable NK1 receptor inhibitor with a pKi of 9.02 in mice. Vofopitant blocks vomiting-related responses and inhibits pseudoptyalism. Vofopitant exerts anxiolytic effects, regulates 5-HT receptor function and increases central 5-HT release. Vofopitant improves hyperarousal symptoms of post-traumatic stress disorder. Vofopitant can be used in research related to depression, anxiety, vomiting and postoperative nausea and vomiting.

HY-B0442AS

Vardenafil-d₅ hydrochloride		98.65%
Vardenafil-d₅ hydrochloride is deuterated labeled Vardenafil hydrochloride (HY-B0442A). Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC₅₀ of 0.7 nM. Vardenafil hydrochloride shows inhibitory towards PDE1, PDE6 with IC₅₀s of 180 nM, and 11 nM, while IC₅₀s are >1000 nM for PDE3 and PDE4. Vardenafil hydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil hydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes^[1]-[6].

HY-17412AS

Minocycline-d₆
Minocycline-d₆ is deuterium labeled Minocycline (HY-17412A). Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect.

HY-W010042S1

L-Glucose-¹³C-1
L-Glucose-¹³C-1 is the ¹³C labeled L-Glucose. L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose can promote food intake.

HY-W738715

Potassium Azide-¹⁵N
Potassium Azide-¹⁵N is the ¹⁵N labeled Potassium Azide (HY-W661390).

HY-W749483

Iprovalicarb-d₈
Iprovalicarb-d₈ is the deuterium labeled Iprovalicarb (HY-121766). Iprovalicarb (Fencaramid; SZX-0722) is a fungicide that can be used for the study of?fungal?diseases in the wine sector.

HY-B2225BS

Starch-¹³C12 (from corn)
Starch-¹³C₁₂ (from corn) is the ¹³ labeled Starch (from corn) (HY-B2225B). Starch (from corn) is a carbohydrate extracted from the kernel of the corn plant. It contains two main components, namely amylose and amylopectin. Starches from corn have various applications in the food industry as thickeners, stabilizers and binders. It is commonly used in the production of products such as baked goods, snacks, sauces and soups. In addition, it can be used as a raw material for the production of biofuels and bioplastics.

HY-W777351

Etravirine-¹³C₃
Etravirine-¹³C₃ (R165335-¹³C₃) is the ¹³C-labeled Etravirine (HY-90005). Etravirine (R165335; TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

HY-41121S2

Boc-L-Ala-OH-2-¹³C
Boc-L-Ala-OH-2-¹³C is a ¹³C-labeled Boc-L-Ala-OH (HY-41121). Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein.

HY-W701234

Propofol Glucuronide₁₇ Methyl Ester
Propofol Glucuronide-d₁₇ Methyl Ester is the deuterium labeled Propofol Glucuronide Methyl Ester.

HY-135399S2

Tauro-obeticholic acid-d₄
Tauro-obeticholic acid-d₄ is the deuterium labeled Tauro-obeticholic acid (HY-135399). Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist.

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